Revolution Medicines, Inc.

Zhican Wang

Mallika Singh

Yu Chi Yang

Justin G Meyerowitz

Ed Lorenzana

W Clay Gustafson

Zhengping Wang

Bojena Bitman

The present disclosure relates to methods for the treatment of diseases or disorders (e.g., cancer) with mTOR inhibitors. Specifically, the disclosure relates to methods of treating a subject having a cancer by administering a particular dosage of an mTOR inhibitor. In some embodiments this disclosure includes methods for delaying, preventing, or treating acquired resistance to RAS inhibitors using a dosage of an mTOR inhibitor. In some embodiments, this disclosure relates to methods of treating or preventing adverse events associated with administration of an mTOR inhibitor using tacrolimus.

Methods of treating cancer with an mTOR inhibitor

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Redwood City, CA, United States of America

Zhican Wang