Shenzhen Chipscreen Biosciences, Ltd.

Shenzhen Chipscreen Biosciences Co., Ltd.

Huawei Technologies Co., Limited

Siemens Aktiengesellschaft

Tsinghua University

Shenzhen Autral Technology Innovation Co., Ltd.

Guangxi Xi Nuo Sheng Glove Co., Ltd.

Chipscreen Biosciences, Ltd.

Huawei Digital Power Technologies Co., Ltd.

Shanghai Jin Feng Yu Glove Co., Ltd.

Zhibin Li

Xianping Lu

Song Shan

Zhiqiang Ning

Xian-Ping Lu

Tuo Deng

Leming Shi

Xianghui Wang

Lijun Xin

Jindi Yu

Qianjiao Yang

Ning Li

Chao Fu

Zhuo Sang

Aihua Xie

Baoshun Ma

Zhende Liu

Chenzhong Liao

Boyu Li

Desi Pan

Jiangfei Zhu

Yonglian Song

Weiming Hu

Markus Vester

Jian Wang

Yu Tang

Jinfeng Li

Yu Zhang

Yan Chen

Xiaoliang Wang

Wenlan Cai

Qinwei Zhang

Huiyun Huang

Weijun Gao

Xingyu Deng

Xiaobin Fan

Qi Wei

Xiangheng Liu

Shengqiong Wang

Long Guo

Haisong Luo

Bingyuan Yang

Adjustable infant highchair

Disclosed are a phenyl amino sodium propionate derivative, a preparation method therefor and an application thereof. Specifically, disclosed are sodium 3-(4-(2-(9H-carbazole-9-yl)ethoxy)phenyl)-2-((2-(4-(4-(2-sodium forrnate-2-((2-(4-fluorobenzoyl)phenyl)amino)ethyl)phenoxy)benzoyl)phenyl)amino)propionate, a preparation method therefor and the use thereof for quality control of a bulk drug or formulation of Chiglitazar or a derivative thereof. Particularly, the compound can be used as a control substance or standard substance for the detection of impurities/related substances in Chiglitazar or a sodium salt drug thereof.

Phenyl amino sodium propionate derivative, preparation method therefor and application thereof

A biphenyl compound represented by formula (I), a preparation method therefor and an application thereof. The present invention also relates to a pharmaceutical composition that comprises the compound as an active ingredient. The compound is a novel small molecule immunomodulator having excellent oral absorption features and can be used for treating and/or preventing various immunity-related diseases.

Biphenyl compound as immunomodulator, preparation method therefor and application thereof

The invention relates to non-solvated crystals A, B and C of N-(2-aminophenyl)-6-(7-methoxyquinoline-4-oxy)-1-naphthamide and preparation methods thereof. The invention also relates to pharmaceutical compositions containing the crystals, and a use of the crystals in preparation of a medicament for the treatment of a disease associated with abnormal protein kinase activity or abnormal histone deacetylase activity.

Non-solvated crystal, preparation method and application thereof

The present invention relates to a urea compound and a preparation method and an application thereof. The structure of the present compound is represented by formula (I), the definition of each variable in the formula being as described in the description. The compound can block interaction between the PD-1/PD-L1 signalling pathways. The compound of the present invention can be used for treating or preventing diseases related to the signalling pathways, such as cancer, autoimmune disease, chronic infectious disease, and other diseases. 

Urea compound and preparation method and application thereof

Disclosed is a method for preparing 2-(2-(4-fluorobenzoyl)phenylamino)-3-(4-(2-(9H-carbazol-9-yl)ethoxy)phenyl)propanoic acid. In the method 9-carbazole ethanol mesylate and methyl 2-[2-(4-fluorobenzoyl)phenyl)amino]-3-(4-hydroxyphenyl)propionate are used as starting materials, and subjected to condensation, hydrolysis and acidification to obtain the target compound. The preparation method of the present invention is suitable for industrial production, and the target compound has a high purity.

Method for preparing phenylalanine compound

The invention discloses a type of fused imidazole compound, preparation method and application thereof. The structure of the compound is shown in general formula I. The definition of each group therein is as described in the specification. These compounds are capable of selectively inhibiting indoleamine 2,3-dioxygenase (IDO). The compounds can act as an IDO inhibitor for treating and/or preventing a disease having a pathological feature with IDO-mediated tryptophan metabolic pathways, for example, cancer, eye disease, autoimmune disease, psychological disorder, depression symptom, anxiety disorder and other diseases.

Fused imidazole compound having indoleamine 2,3-dioxygenase inhibitory activity

A glove includes a glove core and a glove component. The glove core includes a palm portion, a dorsum portion and a side portion of hand. A side of the glove component is adhered on a surface of the glove core, and the glove component covers a part of the palm portion and a part of the dorsum portion of the glove core, a part of the palm portion and a part of the side portion of hand of the glove core, or a part of the dorsum portion and a part of the side portion of hand of the glove core, such that the glove core can be combined with the enhanced glove component, forming a structure which is simple in structure and can be formed easily. Furthermore, the robustness of the glove can be improved significantly to be provided with practicability and progressiveness.

Glove

An application of a compound having general formula (I) as JAK3 and/or JAK1 kinase and a preparation method for the compound.

Preparation method for aromatic heterocyclic compound used as selective JAK3 and/or JAK1 kinase inhibitor and application of aromatic heterocyclic compound

The present invention belongs to the field of pharmaceutical chemistry, and disclosed are two crystal forms of Childamide, that is, Chidamide crystal form A and Chidamide crystal form B, and the method for preparing the new crystal forms of Chidamide. The Chidamide crystal form A and Chidamide crystal form B of the present invention can be used for preparing drugs for treating diseases related to cell differentiation and proliferation.

Crystal form of chidamide, preparation method and use thereof

A body coil includes a first end ring and a second end ring provided at two ends thereof. The first end ring and the second end ring are connected to each other with a plurality of legs. The first end ring or the second end ring has a structure with the current flow width in a direction parallel to the axis thereof being greater than that in a direction perpendicular to the axis thereof. Since the effective action width of the current is increased in the axial direction and the centralized flow of the current in the end ring is reduced, the local specific absorption rate of radio frequency induced by the magnetic field is therefore reduced.

Body coil for magnetic resonance imaging

Isolated compounds of formula I: and stereoisomers, enantiomers, diastereomers, and pharmaceutically acceptable salts thereof are described, as well as processes for production, and methods of use of these compounds and compositions thereof for the treatment of diseases associated with abnormal protein kinase activities and/or abnormal histone deacetylase activities including, for example, inflammatory diseases, autoimmune diseases, cancer, neurological and neurodegenerative diseases, cardiovascular diseases, metabolic disease, allergies and asthma and/or hormone-related diseases.

Naphthamide derivatives as multi-target protein kinase inhibitors and histone deacetylase inhibitors

The present invention relates to Mobile Broadcast Multicast technologies, and discloses a method for subscribing a purchase item in Mobile Broadcast Multicast Service, so that the subscription operation and update operation of the purchase item in BCAST are simplified, and the utilization of system resources is improved. In the present invention, a subscription management module generates a PurchaseItem identification, and sends this identification to a service distribution and adaptation module. Therefore, the PurchaseItem identification may be included in a PurchaseItem fragment sent to a user terminal from the service distribution and adaptation module. And, the function of identifying the purchase item is separated from the PurchaseItem fragment identification. Through sending a service request including the PurchaseItem identification to the subscription management module by the user terminal, the subscription of the purchase item is accomplished. The subscription management module manages service information of the purchase item based on the PurchaseItem identification. A device for implementing the above method is also disclosed in the present invention.

Method and system for subscribing a purchase item in mobile broadcast multicast service

A method and a system for distributing a mobile broadcast service are provided. The method includes: adding header information into broadcast service contents, the header information comprising integrality information and version information of a service packet containing the broadcast service contents; distributing the service packet to a user terminal; updating or accepting, by the user terminal, its own service data by use of the service packet in accordance with the integrality information and version information of the service packet. The method and the system according to the embodiments in the present invention may bring about higher transmission efficiency of data packet.

Method and system for distributing mobile broadcast service and mobile terminal

The present invention is related to the preparation and pharmaceutical use of novel benzamide derivatives as defined in the specification of formula (I) as histone deacetylase inhibitors (HDACI), their preparations and the methods of using these compounds or their pharmaceutically acceptable salt in the treatment of cell proliferative diseases, e.g. cancer and psoriasis. 

Benzamide derivatives as histone deacetylase inhibitors with potent differentiation and anti-proliferation activity

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Guangdong, China

Zhibin Li