The First Affiliated Hospital of Sun Yat-Sen University

School of Data and Computer Science of Sun Yat-Sen University

Zhi Yao

Jian Qi

Xiaolin Liu

Liwei Yan

Qingtang Zhu

Tao Wang

Yao Lu

Tao Lin

Shouliang Liu

The present invention provides a method for three-dimensional reconstruction of fascicular structure of human peripheral nerve, which comprises the steps of: obtaining human peripheral nerve and preparing a peripheral nerve sample; immersing the peripheral nerve sample into a liquid; setting scan parameters of Micro-MRI, scanning the peripheral nerve sample by Micro-MRI, to acquire image data of the peripheral nerve sample in the liquid environment; and three-dimensional reconstructing a structural model of the peripheral nerve sample based on the image data. By means of the method according to the present invention, high-quality scanned images are obtained without destroying the morphology and physical and chemical properties of peripheral nerve, so as to obtain a precise three-dimensional visualization model of peripheral nerve fascicle.

Method for three-dimensional reconstruction of fascicular structure of human peripheral nerve

The present invention provides a method for establishing a biomimetic nerve graft model for nerve fascicles of the extremities, which comprises the steps of: establishing a database of fascicles structures from nerve fascicles of the extremities with an imaging technique; obtaining information of a defective nerve trunk to be repaired of the extremities; and matching and fitting the information of the defective nerve trunk to be repaired of the extremities with/to the data in the database of fascicles structures, to establish a biomimetic nerve graft model that conforms to the characteristics of fascicles microstructure for nerve fascicles of the defective nerve trunk. In the present invention, the imaging technique and clinical data are fully utilized, to establish a biomimetic nerve graft model conforming to the characteristics of fascicles microstructure for varying types of detects, thus providing more accurate model information for repair of nerve trunk defects in the extremities.

Method for establishing biomimetic nerve graft model for nerve fascicles of extremities

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Guangdong, China

Zhi Yao