Toshiba Medical Systems Corporation

Kabushiki Kaisha Toshiba

International Business Machines Corporation

Boe Technology Group Co., Ltd.

Hefei Boe Display Lighting Co., Ltd.

Petrochina Company Limited

Beijing Sig Biopharmaceutical Technology Co., Ltd.

Zhi Yang

Michael D Silver

Alexander A Zamyatin

Yang Yang

Yu Zou

Xue Ping Liu

Yan Zheng

Zhi Zhu

Yinyan Xue

Jane Li

Yang Liu

Satoru Ohishi

Lijun Zhang

Chong Wang

Caineng Zou

Fei Wei

Jinghong Wang

Dejun Li

Lianhua Hou

Yeshun Xu

Jing Huang

Xia Luo

Jingshu Tang

Jingwei Cui

Jingxuan Zhang

Zihan Geng

Xiaoyan Qiu

Hua Zhu

Wenhua Jiang

Suyun Hu

Jinhua Fu

Yejia Qian

Xianyang Liu

Shanzhi Hu

Yongsheng Pan

Senhu Lin

Anusha Muthu-Natarajan

Songtao Wu

IgG epitope and applications thereof as a target are provided. The IgG epitope is the C1 domain of non-B cell-derived IgG, and there is N-glycosylated sialic acid modification at the Asn162 site of the domain. The realization of its antigen functions must depend on the sialylation of the site. The present invention further discloses the applications of the IgG epitope as a drug target in preparing drugs for diagnosis and/or treatment of epithelial tumors. In addition, our studies showed that this antigen depends on the sialylation of Asn162 site as a drug target, and the sialylation of this site must depend on sialyltransferase ST3GAL4, indicating that the enzyme can be used as a drug target for preparing tumor therapeutic drugs. Further, integrin β4 is co-expressed and co-localized with IgG containing the epitope. IgG can be used as a marker for preparing drugs for the auxiliary detection of epithelial tumors.

IgG epitope and applications thereof as a drug target

Embodiments of the present disclosure disclose a shale oil in-situ lightening development method, apparatus and system, wherein the method comprises: determining an effective shale interval according to an interval with a total organic carbon greater than a first lower limit value in a target stratum; determining a favorable region for shale oil in-situ lightening development according to a thickness of the effective shale interval and an effective layer thickness ratio, wherein the effective layer thickness ratio includes a ratio of the thickness of the effective shale interval to a thickness of a shale section, and the shale section includes the effective shale intervals and interlayers therebetween. By utilizing the embodiments of the present disclosure, the benefit of the shale oil in-situ lightening development can be improved.

Shale oil in-situ lightening development method, apparatus and system

Embodiments and processes of computer tomography perform tasks associated with denoising a reconstructed image using an anisotropic diffusion filter and adaptively weighting an iterative instance of the diffused image based upon the product of a weight value and a difference between the iterative instance of the diffused image and the original image. In general, the adaptive weighting is a negative feedback in the iterative steps.

Denoising method and system for preserving clinically significant structures in reconstructed images using adaptively weighted anisotropic diffusion filter

A device, a system, a backlight module and a test method for simulating a light guide plate, the device for simulating a light guide plate includes: a light guide substrate layer; and an electroactive polymer layer, wherein the electroactive polymer layer is formed on the light guide substrate layer and is configured to produce a deformation according to a layout signal of dot-patterns to simulate the dot-patterns.

Device, system, backlight module and test method for simulating light guide plate

Disclosed is a light guide plate, a back plate, an edge-lit type backlight module and a display device. The light guide plate includes a main body and an extending part, wherein the extending part is disposed on a sidewall of the main body and extending outwardly, and the extending part and the sidewall of the main body define a space for accommodating a backlight source.

Light guide plate, back plate, edge-lit type backlight module and display device

A medical imaging apparatus, processing device or specialized circuit can include an input interface to input scan data of a medical image scan of a target object, a processor to generate an output image from the input scan data, and an output interface to output the output image to, e.g., a display. The processor can execute a first reconstruction of the scan data to obtain an intermediate image of the target object, a high-density forward projection of the intermediate object to obtain generated data, a sinogram updating using both of the generated data and the scan data to obtain a high-resolution sinogram, and a second reconstruction based on the high-resolution sinogram to obtain an output image.

High density forward projector for spatial resolution improvement for medical imaging systems including computed tomography

Photon starvation causes streaks and noise and seriously impairs the diagnostic value of the CT imaging. To reduce streaks and noise, a new scheme of adaptive Gaussian filtering relies on the diffusion-derived scale-space concept in one embodiment of the current invention. In scale-space view, filtering by Gaussians of different sizes is similar to decompose the data into a sequence of scales. As the scale measure, the variance of the filter linearly relates to the noise standard deviation of a predetermined noise model in the new filtering method. The new filter has only one optional parameter that remains stable once tuned. Although single-pass processing using the new filter generally achieves desired results, iterations are optionally performed.

Method and system utilizing parameter-less filter for substantially reducing streak and or noise in computer tomography (CT) images

Embodiments and processes of computer tomography perform tasks associated with denoising a reconstructed image using an anistropic diffusion filter and adaptively weighting an iterative instance of the diffused image based upon the product of a weight value and a difference between the iterative instance of the diffused image and the original image. In general, the adaptive weighting is a negative feedback in the iterative steps.

Noise assessment is important to image quality evaluation as well as image processing. For example, the noise level estimation is used as criteria for terminating an iterative noise reduction process. To determine a meaningful noise level, the pixels in featureless regions are separated from the rest of the image. A new concept of pseudo-standard deviation (PSD) is introduced to automatically determine simple and reliable noise level estimates. Furthermore, a histogram of PSD is constructed with fine bins to calculate the moving average of the histogram. The first peak in filtered histogram gives the most representative noise measure as a desired approximation of true standard deviation.

Method and system for estimating noise level

The present application relates to methods for sending an email and distributing an email, and an email server. According to the application, a summary is generated for an email to be sent, with the email stored in a sender side server; the summary of the email is sent to a receiver side server; and the email is sent to the receiver side server in response to receiving, by the sender side server, a request for sending the email, the request being sent by a recipient based on the summary. Thus, the network bandwidth, the storage space of the email server and user terminals may be saved.

Methods for sending an email and distributing an email and an email server

Growing community of inventors

Beijing, China

Zhi Yang