Chinese Academy of Sciences

Mudanjiang Linrun Pharama Excipients Llc.

Zheng Tan

Yuhua Hao

Feng Wang

Yong Zhao

Chen Yang

Jingang Wang

Kewei Zheng

Methods for improving solubility of active pharmaceutical ingredients (APIs) through co-attriting the APIs with select excipients, especially solubility enhancing excipients, and the products prepared by the methods, are disclosed. Pharmaceutical compositions containing co-attrited mixture of an API with a solubility enhancing excipient and use of the pharmaceutical compositions for treatment of diseases or disorders are also disclosed.

Methods of improving pharmaceutical substance solubilization and products thereof

A primer set for detecting telomerase activity, the primer set including a first primer set or a second primer set. The first primer set includes: an upstream primer selected from MTS; and a downstream primer selected from the group consisting of ACX-M4, Beacon ACX62-2C, and Beacon ACX62-10. The second primer set includes: an upstream primer selected from STS or CTS; and a downstream primer selected from the group consisting of ACX, CXT, ACX-M4, Beacon ACX62-2C, or Beacon ACX62-10. The sequences of the primers ACX, CXT, ACX-M4, Beacon ACX62-2C, Beacon ACX62-10, STS, CTS and MTS are shown as SEQ ID NOs: 1 to 8, respectively.

Primer set and method for detecting telomerase activity

A cDNA, including the nucleotide sequence represented by SEQ ID NO: 2. A cDNA, including a nucleotide sequence encoding a complete protein, a protein fragment, a protein analog, or a protein derivative each including the amino acid sequence represented by SEQ ID NO: 1. A cDNA, including the nucleotide sequence encoding the amino acid sequence represented by SEQ ID NO: 1.

Heterogeneous nuclear ribonucleoprotein A2* (hnRNP A2*) and nucleic acid encoding the same

An hnRNP A2* protein, including an amino acid sequence represented by SEQ ID NO: 1. The protein is a complete protein, a protein fragment, a protein analog or a protein derivative.

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Beijing, China

Zheng Tan