State Grid Huzhou Power Supply Company

Zhejiang University

Hangzhou City University

Zhejiang Tianyu Pharmaceutical Co., Ltd.

Zhejiang Province Institute of Architectural Design and Research

Zhejiang Tailun Power Group Co., Ltd.

State Grid Zhejiang Electric Power Co., Ltd. Double Innovation Center

Zhen Wang

Jing Xu

Yongsheng Xu

Weixun Qin

Zhen Chen

Xiaobin Shen

Jie Chai

Feng Zhou

Meng Tang

Wenhui Xu

Yang Zhao

Keqin Ye

Zhi Ding

Yongjun Tu

Xiaojian Wang

Xinlong Wu

Guorong Zhu

Haochuan Qu

Xinhang Chen

Yudong Rui

Jian Wu

Xun Wang

Yueguang Zhang

Weidong Shen

Chenying Yang

Gang Liu

Liupei Wei

Kai Shen

Wei Xiao

Shijun Chen

Chao Ding

Huiping Tang

Liangpeng Che

Size Zhang

Hong Ding

Huaxin Yuan

Xiaowen Zheng

Wen Mu

Wenjia Yuan

Xiaoxiao Wu

Xuelin Yang

Junting Cheng

Kaiyu Zhu

Mengqin Wu

Ruhao Wang

Chongan Pang

Wenlong Xie

Zuwei He

Dequan Su

Ruiyun Lv

Shaojun Xu

Bin Tian

Yingtao Hu

Rongming Huang

Huilin Yang

Provided is a preparation method of losartan, which is prepared by reacting a cyano group-containing intermediate represented by formula (I) with an azide reagent in toluene in the presence of a catalyst; wherein, after the reaction is completed, azide ions are removed by means of the following process: adding water to divide the reaction system into three layers, separating the intermediate layer and adding n-butanol to the intermediate layer for dilution, and adding triphenylphosphine to the resulting diluted solution so as to remove residual azide ions from the diluted solution. The preparation method provided by the present invention does not need to use sodium nitrite, thus fundamentally eliminating the formation of genotoxic impurities nitrosamines. The resulting target product has good purity, high yield, a simple preparation process, mild and easy-to-control operating conditions, and good safety, and is suitable for large-scale industrial production,

Preparation method for losartan

The invention relates to a space curved reticulated shell structure formed by stacking and combining rhombic dodecahedrons, comprising a one-way curved reticulated shell structure, a positive curvature two-way curved reticulated shell structure and a negative curvature two-way curved reticulated shell structure, the array combined revolution body is generated by rotating the orthogonal array combination body around the space rotation axis by a certain angle; boundary cutting structures are generated by the plane boundary in span direction or the curved boundary in span direction cutting the array combined revolution body; the plane boundary cutting structure respectively generates a one-way curved reticulated shell structure, a positive curvature two-way curved reticulated shell structure and a negative curvature two-way curved reticulated shell structure respectively through one-way bending arching, positive curvature two-way bending arching and negative curvature two-way bending arching.

Space curved reticulated shell structure formed by stacking and combining rhombic dodecahedrons and a construction method thereof

A testing device for the internal lateral casting of spatial K-type inclined column grid and the testing method thereof comprises steps: constructing a testing device for the internal lateral casting of spatial K-type inclined column grid; selecting the testing location of the inclined column cross-section; obtaining imaging results of the inclined column cross-section testing locations; determining the concrete quality and taking supplementary testing. The clear module and force transferring route carry out vertical support and column-base fixed limiting measure through overturn-preventing supporting frame and anchoring limiting basis, realize concrete lateral casting and intensity distribution imaging testing through peripheral framework platform and imaging detection device, to effectively improve the lateral casting technology and guarantee bearing performance, realize internal concrete lateral casting construction technology simulation and concrete compactness detection processing simulation, and reach the design intensity and compactness requirement of concrete insides grid inclined column and diagrid cross node.

Testing device for internal lateral casting of spatial K-type inclined column grid and the testing method thereof

A utility vehicle for power emergency repair includes a cab, a carriage and a lighting device, including mounting bases, a wire pole, a rotary base and a lamp assembly. A rotary shaft is bridged between the mounting bases, and the rotary base is fixedly connected to the rotary shaft. First and second positioning units are provided on the top of the carriage. The rotary base has first and second positioning surfaces, the first positioning unit includes a first limiting platform, and the second positioning unit includes a rotation limiting plate and positioning plates. The positioning plates is supported on a lower end surface of the rotation limiting plate. The utility vehicle further includes a driving assembly and first and second contacts. A trigger signal is generated and the driving assembly is controlled to release braking on the rotary shaft when the first and second contacts contact each other.

Utility vehicle for power emergency repair

This disclosure discloses a radiative cooling optical filter, comprising a substrate. One side of the substrate is polished, and the rough side of the substrate is provided with a metal reflective layer. The polished side of the substrate is subsequently provided with the intermediate layers and a top layer. The intermediate layer comprises alternatingly arranged layers A and layers B. The thickness of each layer A and layer B is 50-400 nm. The material of the layer A is silicon dioxide or aluminum oxide, and the material of the layer B is titanium dioxide, silicon nitride or silicon carbide. The material of the top layer is ytterbium fluoride, yttrium fluoride or zinc sulfide. The intermediate layer and the top layer jointly constitute a multi-resonant absorption enhancer in the atmospheric transparent window.

Radiative cooling optical filter, its preparing method and application

Provided is a device for processing an antistress cone of a main insulation layer of a cable. The device includes a support, a clamping unit, a cutting unit and an infeed unit. The clamping unit is mounted on the support and configured to clamp a cable. The cutting unit is slidably disposed on the support, capable of cutting the cable in the radial direction of the cable, and capable of performing feeding in the radial direction of the cable to adjust the cutting depth. The infeed unit is connected to and capable of driving the cutting unit and configured to drive the cutting unit to slide in the axial direction of the cable so that the cutting unit performs feeding and cutting in the axial direction of the cable.

Device for processing an antistress cone of a main insulation layer of a cable

Provided is an insulating coating device for an electric wire, including a pressing pipe. The pressing pipe includes two first pressing parts which are configured to divide the pressing pipe into two parts along a longitudinal cross section of the pressing pipe, an inner wall of the pressing pipe is provided with an air bag, and the air bag is provided with an air pipe joint which penetrates to an outside of the pressing pipe. In the insulating coating device for the electric wire, a self-curing insulating material is coated on joints of the electric wires, the air bag is used to squeeze the self-curing insulating material such that the self-curing insulating material is shaped and compacted, so that cavities generated in a coating process is reduced, and the self-curing insulating material is uniformly attached to the joints of the electric wires.

Insulating coating device for electric wire

A propulsion control device of a 3D printing-based tunnel boring machine, includes two propulsion control modules, and each of which includes tunnel support assemblies, a propulsion control assembly and a barrel body, where a propulsion sliding sleeve is arranged on an outer surface, and several tunnel support assemblies are arranged on an outer side of each propulsion sliding sleeve. Support plates on the two propulsion control modules alternately rise to support a 3D printed tunnel pipe. In the propulsion control module with the support plates in a closed state, a propulsion hydraulic cylinder controls a propulsion hydraulic cylinder extending end to contract, so as to pull the propulsion sliding sleeve to a front section of the barrel body; and in the propulsion control module with the support plates in a support state, the barrel body continuously advances relative to the propulsion sliding sleeve.

Propulsion control device of tunnel boring machine for 3D printing a tunnel

The present disclosure relates to the technical field of cable processing, and discloses a method for processing a reaction force cone of a cable main insulating layer. The method includes: two ends of a cable are clamped through a clamping device, and the cable is enabled to pass through a cutting device; a cutting depth of the cutting device in a radial direction and a cutting position of the cutting device in an axial direction are adjusted; the cutting device is started, and the cable is cut by the cutting device to form the reaction force cone.

Method for processing a reaction force cone of a cable main insulating layer

The present invention discloses a method for preparing an anti-heart-failure medicine LCZ696. The preparing method comprises the following step (formula (I)): in an organic solvent, a Sacubitril dicyclohexylamine salt reacts with valsartan under the effect of a sodium hydroxide aqueous solution, and the anti-heart-failure medicine LCZ696 is obtained. The preparing method of the present invention is simple in process and omits the procedures of ion exchange from a sodium salt to a calcium salt and hydrochloric acid dissociation in an existing production process, residues of calcium ions are avoided, and the production efficiency is effectively improved.

Method for preparing anti-heart-failure medicine LCZ696

Growing community of inventors

Zhejiang, China

Zhen Wang