California Institute of Technology

Zhen Liu

Kai Chen

Gian Franco Sacco

Paul A Rosen

Mark Simons

Costin Radulescu

Piyush Shanker Agram

Frank H Webb

Brian D Wilson

Eric Jameson Fielding

Noah P Dunham

Daniel J Wackelin

Sang Ho Yun

Jennifer W Cruz

Andrew Z Zhou

Angelyn W Moore

Hook Kian Hua

Paul Randall Lundgren

Gerald John Maramba Manipon

Susan Ethel Owen

Timothy M Stough

Michael David Starch

The present disclosure provides cytochrome P450 variants useful for carrying out in vivo and in vitro carbene insertion reactions. Methods for preparing carbene insertion products including cyclopropenes, cyclopropanes, bicyclobutanes, substituted lactones, cyclized compounds, and substituted amines are also described.

Diverse carbene transferase enzyme catalysts derived from a P450 enzyme

Many embodiments provide a hybrid data processing system (HySDS) of an end-to-end geodetic imaging data system enabling near-real-time science, assessment, response, and rapid recovery. The HySDS may be an operation data processing system that integrates data from many different geodetic data sources and/or sensors, including interferometric synthetic aperture radar (InSAR), GPS, pixel tracking, seismology, and/or modeling, and processes the data to generate actionable high quality science data products. The HySDS may provide for an automated imaging and analysis capabilities that is able to handle the imminent increases in raw data from new and existing geodetic monitoring sensor systems.

Systems and methods for advanced rapid imaging and analysis for earthquakes

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Pasadena, CA, United States of America

Zhen Liu