Leica Microsystems Ltd., Shanghai

Leica Biosystems Nussloch Gmbh

Zheguang Fan

Xiang Liang

Gang Zhou

Jingtian Zhang

Xiaoqi Jiang

Xiao Zhou

Xiangyu Hao

Yunchao Yang

Jinyu Xu

Song Jin

The present disclosure relates to a cutter holder for a microtome. The cutter holder includes: a base; a pressing plate pivotably mounted to the base and having a first end configured to clamp the cutter; an eccentric shaft rotatably mounted in the base; and a sliding assembly slidably mounted in the base. The sliding assembly is arranged between the pressing plate and the eccentric shaft and is in contact with the eccentric shaft, and the sliding assembly is movable towards the pressing plate when the eccentric shaft rotates, so as to force the first end of the pressing plate to clamp the cutter with the base. The cutter holder according to embodiments of the present disclosure allows easy mounting and replacement of the pressing plate, facilitates clamping of the cutter and regulation of a clamping force, and has high working efficiency and high reliability.

Cutter holder for microtome

The present disclosure provides a blade load mechanism for a blade holder of a microtome. The blade holder has a base defining a blade receptacle configured to receive a blade, the blade load mechanism includes a blade supply container configured to contain a blade therein, the blade supply container defining a removal opening through which the blade is able to be removed from the blade supply container, and a blade access slot through an outer wall of the blade supply container in a length direction of the blade; and a blade pusher configured to engage with the blade through the blade access slot and slide along the blade access slot to push the blade out of the blade supply container through the removal opening, and deliver the blade into the blade receptacle. The present disclosure further provides a blade unload mechanism and a blade changing system.

Blade load mechanism, blade unload mechanism and blade changing system

A retraction device includes a spindle movable along the axis thereof and an operating unit including a pull rod and a movable member. The movable member defines a step-shaped groove, the pull rod has a first end connected to the spindle, and a second end received in the groove; the groove includes a first step and a second step and an inclined face connecting the first step and the second step arranged along a first direction, and a height of the second step is greater than that of the first step along the axis direction of the spindle; the movable member is slidable along the first direction relative to the pull rod, to allow the spindle to switch between a retraction position in which the pull rod is received in the second step, and a release position in which the pull rod is received in the first step.

Retraction device and feed mechanism having the same

A retraction device includes: a spindle, a support plate and a plurality of spring washers. The spindle is movable along an axis direction thereof and has a first end; a support plate has a fixed position, the first end of the spindle penetrates the support plate; and the plurality of spring washers are fitted over the first end of the spindle and stacked together in an identical direction. The plurality of spring washers are compressed between the spindle and the support plate with a predetermined pre-load. The spindle is configured to be switchable between a first position and a second position, and capable of moving a predetermined distance relative to the support plate in the axis direction of the spindle during switching. When in the first position, the spindle is farthest from the support plate, when in the second position, the spindle is closest to the support plate.

The disclosure relates to a microtome having a cutting knife, an object holder mounted on a slide, the slide being movable relative to the cutting knife in a cutting direction and in a thickness defining direction, movement of the slide in the thickness defining direction being performed by a first electric motor controlled by a control unit, movement of the slide in the cutting direction being performed by a second electric motor controlled by the control unit, wherein the control unit is configured to control the movement of the slide in the thickness defining direction and in the cutting direction.

Controlling a motorized microtome

A clamping device includes: an operating member; a wedge having a first inclined surface; a clamping member having a second inclined surface movable relative to the first inclined surface, the first and second inclined surfaces being provided in a face-to-face arrangement; and a housing having a first guiding part, a second guiding part and a chamber. The operating member is mounted in the first guiding part, the clamping member is mounted in the second guiding part, and the wedge is disposed in the chamber; the operating member is operated to move towards the wedge, such that the operating member contacts and pushes the wedge to move, and further the first inclined surface contacts and moves along the second inclined surface; whereby a pushing force of the operating member in a first direction is converted into a clamping force of the clamping member in a second direction.

Clamping device and microtome having same

A rotary microtome and a control method therefore are provided. The rotary microtome includes: a specimen holder, configured to hold a specimen; a handwheel drive system, including a handwheel and a handwheel axis, and configured to receive a user operation via the handwheel and to move the specimen holder up and down via the handwheel axis based on the user operation; a damping component, connected to the handwheel axis, and configured to generate damping for rotation of the handwheel axis; a knife; a section motor, connected to the knife and configured to drive the knife to cut the specimen; and a control device, connected to the damping component and the section motor respectively, and configured to obtain an operation parameter of the section motor, and to adjust the damping generated by the damping component according to the operation parameter, such that the user feels a material hardness of the specimen.

Rotary microtome and control method for the same

A mass-balance means and a rotary microtome having the same are provided in the present disclosure. The mass-balance means includes: a connecting element, a first end of the connecting element being configured to be connected with a movable mass of the rotary microtome; a gear set having a preset gear ratio, a first end of the gear set being connected with a second end of the connecting element; an elastic element, the elastic element being pre-tensioned and adjustable, in which a first end of the elastic element is connected with a second end of the gear set for moving along with a rotation of the gear set so as to balance the movable mass.

Mass-balance means and rotary microtome having same

Microtome

Control panel

A mass-balancing arrangement comprises an adjustably pre-loaded spring member (); a pivotably mounted lever () for compensating different inertial forces in combination with the spring member (); a first drawing member () connecting a movable mass to the lever (); a second drawing member () connecting the spring member () to the lever (); and a first roller () for deflecting the first drawing member (). The lever () has an upper lever arm () and a lower lever arm (), one being sector-shaped and the other cam-shaped. The upper lever arm is connected to the movable mass through the first drawing member (), and the lower lever arm is connected to the spring () through the second drawing member (). Two torques produced at the upper and lower lever arms are kept balanced. The balanced mass may be an object carriage of a microtome.

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Shanghai, China

Zheguang Fan