U-systems, Inc.

Acellent Technologies, Inc.

Karssemeijer, Nico

Zengpin Yu

Shih-Ping Wang

Thomas Neff

Wei Zhang

Jiayu Chen

Donald Chin

Tommy Earl Cupples

Danhua Zhao

Michael E Reed

Shengtz Lin

Shawn J Beard

Irene Li

Xinlin Qing

Fangyi Rao

Tor Collins Anderson

Douglas G Summers

Bao Liu

Feng Yin

Jeanine M Rader

David C Zhang

Eddy Ye

A modular, flexible architecture for offering full-field breast ultrasound (FFBU) functionality and general-purpose ultrasound functionality in a single system is described. A conventional, general-purpose ultrasound system is modified with an FFBU toolkit to create a dual-capability ultrasound system, the dual-capability ultrasound system being able to accommodate both general-purpose ultrasound functionality and FFBU functionality, using a single ultrasound engine. Among other advantages, real-world clinical environments may enjoy cost savings for initial system procurement, space savings on clinic floors, easier and less expensive system upgrades, and the ability to use a single system and user interface for both FFBU screening and for follow-up diagnosis, biopsy, etc. Among other advantages from an ultrasound manufacturer's perspective are the ability to quickly and/or more easily come to market with an FFBU-related offering by modifying their existing general-purpose ultrasound systems with FFBU toolkits to quickly create dual-capability ultrasound systems.

Full-field breast ultrasound system and architechture

Navigation among breast ultrasound volumes derived from different volumetric ultrasonic scans of a same breast is described. On a display of a breast ultrasound workstation, a first image derived from a first ultrasonic volume is displayed. A user election of a source region of interest (ROI) in the first image is received. A destination ROI within a second ultrasonic volume is identified that at least roughly corresponds to a same locality of tissue in the breast as the source ROI. A second image derived from the second ultrasonic volume and including the destination ROI is displayed, the destination ROI being highlighted.

Breast ultrasound examination including scanning through chestwardly compressing membrane and processing and displaying acquired ultrasound image information

A modular, flexible architecture for offering full-field breast ultrasound (FFBU) functionality and general-purpose ultrasound functionality in a single system is described. A conventional, general-purpose ultrasound system () is modified with an FFBU toolkit to create a dual-capability ultrasound system (), the dual-capability ultrasound system () being able to accommodate both general-purpose ultrasound functionality and FFBU functionality, using a single ultrasound engine (). Among other advantages, real-world clinical environments may enjoy cost savings for initial system procurement, space savings on clinic floors, easier and less expensive system upgrades, and the ability to use a single system and user interface for both FFBU screening and for follow-up diagnosis, biopsy, etc. Among other advantages from an ultrasound manufacturer's perspective are the ability to quickly and/or more easily come to market with an FFBU-related offering by modifying their existing general-purpose ultrasound systems () with FFBU toolkits to quickly create dual-capability ultrasound systems ().

Full-field breast ultrasound system and architecture

A system, computer program product, and related methods are described for obtaining, processing, and/or and archiving full-field breast image data, such as full-field breast ultrasound (FFBU) data, in a manner that promotes ready integration with current x-ray mammogram-based breast cancer screening methodologies, and which can alternatively be used to support a full-field-only environment. Two-dimensional thick-slice images computed from a three-dimensional data volume are used to facilitate efficient archiving for a breast imaging session, the two-dimensional thick-slice images corresponding to slab-like subvolumes of the breast. Clinician data overload problems that can arise from the existence of large amounts of three-dimensional full-field breast image data are reduced. Archive space is also preserved while still providing sufficient information data for future reference purposes. Related adjunctive full-field workflow methods are also described. The described embodiments are applicable to FFBU imaging and other full-field breast imaging modalities such as MRI, CT, PET, and others.

Full-field breast image data processing and archiving

Displaying breast ultrasound information on an interactive user interface is described, the user interface being useful in adjunctive ultrasound mammography environments and/or ultrasound-only mammography environments. Bilateral comparison is facilitated by a pairwise display of thick-slice images corresponding to analogous slab-like subvolumes in the left and right breasts. Coronal thick-slice imaging and convenient navigation on and among coronal thick-slice images is described. In one preferred embodiment, a nipple marker is displayed the coronal thick-slice image representing a projection of a nipple location thereupon. A convenient breast icon is also displayed including a cursor position indicator variably disposed thereon in a manner that reflects a relative position between the cursor and the nipple marker. Preferably, the breast icon is configured to at least roughly resemble a clock face, the center of the clock face representing the nipple marker location. Bookmark-centric and CAD-marker-centric navigation within and among thick-slice images is also described.

Thick-slice ultrasound images derived from ultrasonic scans of a chestwardly-compressed breast of a supine patient

A method for optimizing transducer performance in an array of transducers in a structural health monitoring system includes specifying a plurality of paths between pairs of the transducers on a monitored structure and evaluating the quality of signal transmissions along the paths so as to optimize the gain and frequency operating condition of the transducers.

Functional actuator-sensor path optimization in structural health monitoring system

Coronal and axial thick-slice ultrasound images derived from ultrasonic scans of a chestwardly-compressed breast

Processing and displaying breast ultrasound information

Use of a single line for switching multiple monitoring elements on/off, and a single line for sending signals to, or receiving signals from, those elements that are switched on. Monitoring elements each have an associated switching element, and each switching element is connected to a common switching line, or control line. A signal from the control line turns each switch on or off. Each monitoring element is also connected to a single signal line, and only those monitoring elements that are turned on can transmit/receive data signals along this signal line.

Method and apparatus for switching among elements of a structural health monitoring system

An ultrasound information processing system comprises a plurality of ultrasound devices coupled to a high-speed serial ultrasound information bus, wherein each ultrasound device comprises a program for communicating with other ultrasound devices according to an ultrasound information exchange protocol (UIEP). The UIEP is a lightweight, connection-oriented protocol adapted to efficiently transfer ultrasound information among different devices on the ultrasound information bus. Each ultrasound device comprises an application layer program for performing an ultrasound function, as well as a lower protocol layer program for receiving and sending data across the ultrasound information bus according to a high-speed serial bus standard that provides both isochronous and asynchronous data delivery. The ultrasound information exchange protocol (UIEP) program is adapted to receive a communication request from the application layer, open a connection-oriented communication session with the requested ultrasound device, and transfer ultrasound information through the lower protocol layer and across the ultrasound information bus to the requested device. Advantageously, any ultrasound device manufacturer provided with the UIEP program may readily generate application layer code capable of communicating with other manufacturers' ultrasound devices across the ultrasound information bus, without requiring specific knowledge of the internal structure of the other manufacturers' devices or of the specific frame/packet structure of the UIEP/lower layer protocols themselves.

Ultrasound information processing system and ultrasound information exchange protocol therefor

An architecture and protocol are provided for allowing flexible, low cost, and upgradable ultrasound information processing systems. Ultrasound information processing functions are performed by a plurality of ultrasound modules coupled to a high-speed, multiple-drop serial ultrasound information bus. The ultrasound information bus is used for packetized data transfer among the ultrasound modules in accordance with an ultrasound information exchange protocol. Additional or upgraded ultrasound modules are designed to connect to the ultrasound information bus and to communicate using the ultrasound information exchange protocol. Thus, according to a preferred embodiment, as improvements in hardware technology or software algorithms are made, additional or upgraded ultrasound modules are simply &ldquo;plugged in&rdquo; to the ultrasound information bus, hereby reducing costs and increasing system versatility and upgradability.

Ultrasound information processing system

An ultrasound system that generates compound images from component frames having decorrelated speckle patterns. Successive sets of distinct, speckle-affecting parameters are used to generate successive component frames for compounding, and are selected such that the successive component frames have decorrelated speckle patterns. The speckle-affecting parameters that are changed from frame to frame may be selected from a wide variety of parameters, including transmit beamformer parameters, receive beamformer parameters, and demodulator parameters. According to a preferred embodiment, the successive sets of speckle-affecting parameters differ from each other by at least two speckle-affecting parameters. According to another preferred embodiment, the amount by which each of the multiple speckle-affecting parameters is changed is less than a decorrelation threshold for that parameter, that is, by less that the amount that speckle-affecting parameter alone would be required to change in order to yield decorrelated speckle patterns if no other parameters were changed. When more speckle-affecting parameters are changed, each speckle-affecting parameter can be changed by an amount less than its decorrelation threshold, and yet decorrelated speckle patterns can still be obtained. Moreover, because two different types of speckle-affecting parameters tend to alter the spatial resolution of the component frames in different ways, the spatial resolution of the compounded image can be better as compared to the scenario in which only one speckle-affecting parameter is altered by its decorrelation threshold.

Method and system for generating ultrasound frames with decorrelated speckle patterns and generating a compound ultrasound image therefrom

A method, system, computer program product, and user interface for real-time ultrasonic visualization enhancement of a biopsy needle are disclosed in which a wide range of needle positions with respect to the ultrasound probe axis and with respect to the imaged plane are accommodated. Ordinary frames are compounded with special purpose frames, the special purpose frames having transmit and receive parameters adapted to highlight reception of echoes from the biopsy needle. Preferably, an elevation beam width associated with the special purpose ultrasound frames is wider than an elevation beam width associated with the ordinary ultrasound frames. Preferably, the beams of the special purpose ultrasound frames are steered such that they are incident upon the biopsy needle at an increased angle as compared to the angle of incidence for ordinary ultrasound frames. A method for automatically and adaptively determining the depth and orientation of a biopsy needle is also described, whereby beam steering parameters, focus parameters, etc. may be automatically and adaptively computed. The user may optionally provide selected beam steering parameters to the ultrasound imaging system using a simple, intuitive user interface.

Growing community of inventors

Palo Alto, CA, United States of America

Zengpin Yu