Histosonics, Inc.

Zeljko Mladenovic

Joshua Stopek

Ryan M Miller

Alexander P Duryea

Jonathan M Cannata

Dejan Teofilovic

Aleksandra Rakic

Erin-Anne Lemieux

Carol L Shaffer

Joshua A King

Carolyn M Turner

Viktor Bollen

Vladimir Perovic

A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.

Histotripsy systems and methods

A system and method, including an ultrasound imaging transducer, an ultrasound therapy transducer, a robotic arm configured to orient the ultrasound imaging transducer and the ultrasound therapy transducer about a patient, a display connected to imaging transducer, and a memory, storing instructions that when executed by a processor receive ultrasound images from the imaging transducer, present ultrasound images, receive an input to alter a shape of a contour line, present the contour line, receive an input of a size of a margin around the treatment area, present the margin, determine end points at locations where X, Y, and Z axes bisect the contour line in an XZ plane and a YZ plane, drive the ultrasound therapy transducer to a location where a focal point of the ultrasound therapy transducer is at the end point, and determining whether a resistance to movement exceeds a threshold.

Histotripsy systems and associated methods including user interfaces and workflows for treatment planning and therapy

Display screen or portion thereof with an animated graphical user interface

Growing community of inventors

Ann Arbor, MI, United States of America

Zeljko Mladenovic