Ceskoslovenska Akademie Ved

Zdenek Plichta

Miroslav Bleha

Eva Votavova

Jaroslav Kalal

Polymers containing a reactive aromatic system in the side chain which consist of structural units of the general formula IV: ##STR1## where R.sup.1 is hydrogen or CH.sub.3,

Polymers containing a reactive aromatic system based on

Polymeric color pH indicators are prepared which are insoluble in the measured aqueous medium and show a certain range of color change. These polymeric indicators are the product of copolymerization of a hydrophilic comonomer, selected from esters, amides and N-substituted amides of acrylic and methacrylic acid, with 0.1- 30 wt.% of a comonomer. The comonomer forms the pH-indicating color center by a subsequent coupling with a suitable diazonium salt or a passive component. Vinylic monomers comprising an aromatic system in the molecule are suitable as the functional comonomers. The indicators are prepared by radical copolymerization of the comonomers either in a suspension or in a solution, followed by the subsequent coupling with a diazonium compound, or diazotizing and coupling with a passive component, to obtain the pH-indicating sites of polymer. The product is in the form of small spherical macroporous particles suitable for pH indication in flow-through column processes, in small volumes, or on a microscope stage, or in the form of a solution applicable as a paint and indicating the pH of vessels, reactors, etc. coated therewith, or useful for application to inert carriers.

Polymeric color indicators and a method of their preparation

The invention relates to monomers of the general formula I with a reactive aromatic system based on p-phenylenediamine derivatives:

Monomers and polymers containing the reactive aromatic system and method

The invention relates to biologically active insoluble compounds on a carrier containing in its side chains a p-phenylene-diamine skeleton, where a polymer of the general formula I ##STR1## where R.sub.1 is a polymer residue, R.sub.2 is a lower alkyl group, x = 1-4, is oxidized in the presence of a soluble biologically active compound containing a primary amino group, such as e.g. enzymes, coenzymes, inhibitors of enzymes, hormones, or antigens. The oxidation is carried out by using an oxidation agent which does not disturb the biologically active compounds present in the mixture.

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Prague, Czechia

Zdenek Plichta