Dnae Group Holdings Limited

Other

Cambridge Gan Devices Limited

Zahid Ansari

Christofer Toumazou

Samuel Reed

Alpesh Patel

Kurt Kolb

Daniel Morley

Leila Shepherd

Krishna Amin

Ginny Jorgensen

Florin Udrea

Loizos Efthymiou

Martin Arnold

John William Findlay

Sheung Wai Fung

Sam Reed

Francois Paillier

Christopher Maurice Neville Tofts

Wai Hon Ng

Peter Charles Howard

A semiconductor switch comprising a first main terminal, a second main terminal, and a control terminal, the semiconductor switch further comprising: a III-nitride high-electron-mobility transistor (HEMT), the III-nitride HEMT comprising a first source terminal, a first drain terminal, and a first gate terminal; a first interface circuit operatively connected to the control terminal and to the first gate terminal; and a short-circuit detection circuit operatively connected to the first drain terminal and the first source terminal, the short-circuit detection circuit being configured to: sense a short-circuit across the first drain terminal and the first source terminal; and transmit a short-circuit detection signal to the first interface circuit, the first interface circuit being configured, upon receipt of the short-circuit detection signal, to cause the III-nitride HEMT to turn off, and/or to cause a voltage across the first gate terminal to be reduced.

Semiconductor switch comprising a short-circuit detection circuit

A method for increasing the number of analyte/assay combinations in a single chip or cartridge of an in vitro diagnostic system may include: prioritizing a set of analyte/assay combinations based on characteristics of each analyte in the set of analyte/assay combinations, wherein the characteristics comprise one selected from the group consisting of a prevalence of each analyte, a clinical relevance of each analyte, a clinical actionability of each analyte, a patient benefit, a cost savings, and any combination thereof; deriving an analyte/analyte interactivity for two or more analytes in the set of analyte/assay combinations; designing a plurality of candidate panel layouts based on panel layout rules, the prioritization of the set of analyte/assay combinations, and the analyte/analyte interactivity, wherein the panel layout comprises one or more chips each comprising a chamber with two or more analytes; and validating the plurality of candidate panel layouts to produce panel layout solutions.

Methods for preparing cartridges for in vitro diagnostics and related systems

An assay device () is provided. The device comprises an integrated circuit (IC) () comprising a plurality of ISFETs (); an over-moulded layer () which partially covers the IC, such that the plurality of ISFETs remain uncovered; and a film () provided across substantially the entire IC. The film acts as a passivation and/or sensing layer for each of the ISFETs. In addition, the film acts as a barrier layer to encase the over-moulded layer.

Packaging for integrated circuits

Provided is a sensing apparatus comprising a chip for integrated amplification and sequencing of a template polynucleotide in a sample. The apparatus comprises a chip with at least one ISFET in a well or chamber, amplification means for amplifying the template polynucleotide on a surface of said chip and comprising at least one heating means suitable for conducting amplification of the template polynucleotide at temperatures elevated with respect to room temperature, and sequencing means for sequencing the amplified template polynucleotide in said well or chamber. Methods of use are also provided.

Sensing apparatus for amplification and sequencing of template polynucleotides and array for amplification of template polynucleotides

A startup circuit delivers regulated startup current to a control IC in a switched-mode power supply (SMPS) system, and automatically disconnects the startup current when the SMPS Control IC starts switching the transformer or inductor used as the energy storage element in the SMPS system. Disconnection of the startup current may be triggered by detecting a time-varying voltage waveform on an accessible node in the SMPS system, or by detecting an increased current consumption by the SMPS Control IC, without requiring any ground reference to the SMPS Control IC, nor without requiring any logic signals generated by the SMPS Control IC. This provides for rapid and predictable startup of an SMPS Control IC and reduced power loss once the SMPS Control IC is operational, and is independent of the operating voltages of the SMPS control IC, and independent of the particular control scheme and switch topology of the SMPS system.

Switched-mode power supply startup circuit, method, and system incorporating same

Growing community of inventors

Cambridge, United Kingdom

Zahid Ansari