Cardiacassist, Inc

Cardiac Assist Technologies, Inc.

Zafiris G Zafirelis

John C Marous, Iii

Yih-Choung Yu

Kirk A Lehmann

Greg A Johnson

Gregory A Johnson

Greg A John

John C Marous

John C Iii Marous

A method of providing a pumping system for assisting a human patient's heart and providing a blood pump to be disposed outside the patient's body is disclosed. The blood pump has an inlet and an outlet. An inlet cannula is provided for insertion percutaneously into the vascular system of the patient, and is adapted to be placed in fluid communication with the blood pump inlet to provide blood to the blood pump. An outlet perfusion cannula is provided for insertion percutaneously into the vascular system of the patient, and is adapted to be placed in fluid communication with the blood pump outlet to provide blood to the patient's vascular system. The blood pump includes a control system to control the blood pump. The control system includes at least two control units for redundant control of the blood pump, and each control unit includes a watchdog for monitoring the control unit.

Method and system for closed chest blood flow support

A pumping system for assisting a patient's heart includes a blood pump disposed outside the patient's body and having an inlet and an outlet. An inlet cannula is configured for insertion percutaneously into the vascular system of the patient, and in fluid communication with the blood pump inlet to provide blood to the blood pump. An outlet perfusion cannula is configured for insertion percutaneously into the vascular system of the patient, and in fluid communication with the blood pump outlet to provide blood to the patient's vascular system. A control system is provided to control the blood pump and includes at least two control units for redundant control of the blood pump. Each control unit includes a watchdog for monitoring the control unit. A variation of the pumping system includes a bidirectional cannula for insertion percutaneously into the vascular system of the patient and to extend into the patient's heart.

A system for assisting flow of blood by a patient's heart. The system includes a transseptal cannula adapted to be inserted percutaneously in the jugular vein and extend through the atrial septum from the right atrium to the left atrium. The system includes a blood pump mechanism having a blood pump for pumping blood received from the transseptal cannula that has been oxygenated at specified flow rates over a range of physiological pressures. The blood pump is connected to the transseptal cannula. The system includes a perfusion cannula adapted to be inserted percutaneously in the axillary artery for returning oxygenated blood to the atrial system of the patient. The perfusion cannula is connected to the blood pump. A method for assisting blood flow by a patient's heart. The method includes the steps of inserting percutaneously in the jugular vein of the patient and extending through the atrial septum from the right atrium to the left atrium a transseptal cannula. Next there is the step of inserting percutaneously in the axillary artery a perfusion cannula for returning oxygenated blood to the arterial system of the patient. Then there is the step of pumping blood with a blood pump connected to the transseptal cannula and the perfusion cannula at specified flow rates over a range of physiological pressures.

A system for assisting flow of blood by a patient's heart. The system includes a transseptal cannula adapted to be inserted percutaneously in the femoral vein and extend through the atrial septum from the right atrium to the left atrium. The system includes a blood pump mechanism having a blood pump for pumping blood received from the transseptal cannula that has been oxygenated at specified flow rates over a range of physiological pressures. The blood pump is connected to the transseptal cannula. The system includes a perfusion cannula adapted to be inserted percutaneously in the femoral artery for returning oxygenated blood to the atrial system of the patient. The perfusion cannula is connected to the blood pump. A method for assisting blood flow by a patient's heart. The method includes the steps of inserting percutaneously in the femoral vein of the patient and extending through the atrial septum from the right atrium to the left atrium a transseptal cannula. Next there is the step of inserting percutaneously in the femoral artery a perfusion cannula for returning oxygenated blood to the arterial system of the patient. Then there is the step of pumping blood with a blood pump connected to the transseptal cannula and the perfusion cannula at specified flow rates over a range of physiological pressures.

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Needham, MA, United States of America

Zafiris G Zafirelis