Riom Laboratories C.e.r.m.

Riom Laboratories C.e.r.m. 'rl-c.e.r.m.' S.a.

Yvon Bernet

Michel Combourieu

Nadine Simbille

Jean-Claude Laigle

Marie-Paule Landes

N,N-dimethyl-N'-benzoyl-N'-(2,3-dihydrobenzofuran-2-ylmethyl)1,3-propanedia mine of formula: ##STR1## and its pharmaceutically acceptable salts, in racemic form or in the form of enantiomers, which compounds have anti-arrhythmic properties.

1,3-propanediamine derivatives and antiauhythnic pharmaceutical

The invention is dealing with antispasmodic compounds of the formula I ##STR1## in which R.sub.1 denotes H, halogen or a linear or branched C.sub.1 to C.sub.3 alkoxy or alkyl group, R.sub.2, R.sub.3 and R.sub.4 separately denote a linear or branched C.sub.1 to C.sub.4 alkyl group or R.sub.2 and R.sub.3 together with the nitrogen atom to which they are bound form a saturated heterocyclic radical, Z denotes a linear or branched C.sub.1 to C.sub.6 alkylene group and X.sup.- denotes an anion, preferably a halogen ion, and is dealing with intermediates in the preparation of the compounds of formula I.

Growing community of inventors

Jussac, France

Yvon Bernet