Adir Et Compagnie

Les Laboratoires Servier

Adir Et Cie

Yves Rolland

Jacqueline Bonnet

Michel Wierzbicki

Jean-Daniel Brion

Armel Fradin

Luc Demuynck

Pietro Ghezzi

Lucy De Montarby

Anne-Marie Chollet

Tony Verbeuren

Emmanuel Canet

Bernard Testa

Marie-Francedillaoise Boussard

Guy Lewin

Jean-Paul Tillement

Alain Pierre

Ghanem Atassi

Jean-Paul Vilaine

Jean Lepagnol

Alain Dhainaut

Serge Simonet

Michel Koch

Catherine Thollon

Marie-Odile Vallez

Michel Lonchampt

Albert Lenaers

Francedillaois Tillequin

Jacques DuHault

Danielle Gree

Serge Labidalle

Alexios-Leandros Skaltsounis

Ren E Gree

Ali M Hachem

Yves Le Floc'h

Aime Crevat

Daniel Guyot

Strontium salts of the sulphonic acids of formula (I):A-B&#x2014;SOH&#x2003;&#x2003;(I), Medicinal products containing the same which are useful in the treatment of osteoarthritis and osteoporosis.

Strontium salts of sulphonic acids, a process for their preparation and pharmaceutical compositions containing them

A compound of general formula (I): ##STR1## in which: R.sub.1 represents alkyl,

Flavone compounds

A compound of formula (I): ##STR1## In which: R.sub.1 represents linear or branched (C.sub.1 -C.sub.6) alkyl,

N-benzylpiperazine compounds

A compound of formula (I): ##STR1## in which X, n, B and Y are as defined in the description. useful as cytokine inhibitors.

Heterocyclic compounds

Disclosed herein are new diosmetin compounds of formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are as defined in the description. The said compounds are useful in the treatment of chronic venous insufficiency.

Diosmetin compounds

A compound selected from those of formula (I): ##STR1## wherein A, X, Y, Z, R, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined in the description. This compound or its physiologically tolerable salts may be used therapeutically as platelet anti-aggregation agent.

Cyclised analogues of fatty acid metabolites

New benzothiazine derivatives corresponding to the general formula I: ##STR1## in which: X represents halogen,

Phenothiazine cytokine inhibitors

Compounds of formula (I): ##STR1## wherein R.sub.3, R.sub.4, R.sub.5, R.sub.6, X and Y are defined in the description. Those compounds are used therapeutically in the treatment of cancerous tumours.

Acronycine analogues

The compounds are N-(unsubstituted or substituted) N'-benzylpiperazine compounds and pharmaceutically tolerable salts thereof, useful for treating neuronal disorders resulting from the dysfunctioning of oxidative metabolism. A compound disclosed is: N-ethyl N'-(2-hydroxy-3,4- dimethoxybenzyl)-piperazine and its dihydrochloride.

Compounds of the general formula (I): ##STR1## in which R represents: a hydrogen atom, or a radical --OR' in which R' is as defined in the description.

3',5'-di-tert.-butyl-4'-hydroxy flavones

Compound of general formula I: ##STR1## in which: A is a single or double bond,

2-(piperazinyl)-2-oxoethylene-substituted flavonoid compounds

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Vanves, France

Yves Rolland