Aventis Pharma S.a.

Aventis Cropscience S.a.

Rhone-poulenc Agro

Scynexis Chemistry & Automation, Inc.

Yves Ribeill

Eric Bacque

Jean-Claude Barriere

Susan Marie McComb

Scot Kevin Huber

Pascal Desmazeau

Michael James Malaska

Baptiste Ronan

David Teh-Wei Chou

Adalberto Perez De Leon

Jean Bouquerel

Gilles Dutruc-Rosset

Daniel Achard

Gilles Doerflinger

Serge Grisoni

Jean-Pierre Leconte

Gérard Puchault

David T Chou

Herv&eacute; Bouchard

Adalberto A Perez De Leon

Corinne Terrier

Alain Commer&ccedil;on

Jaleh Abedi

G&eacute;rard Puchault

Henry David Smith, Iii

Pierre Monnet

Group A streptogramin derivatives of general formula (I) in which: 

Streptogramin derivatives, their preparation and compositions containing them

A method of controlling parasites in or on an animal comprising orally administering to the animal a parasiticidally effective, substantially non-emetic 1-arylpyrazole.

Control of arthropods in animals

Group B streptogramin derivatives of general formula (I) are disclosed:wherein Ra, Rb, Rc, Rd, R, Rand Y are as defined in the description, including preparation methods and compositions containing the same. Such derivatives are particularly useful as antimicrobial agents, optionally combined with at least one group A streptogramin derivative.

Streptogramin derivatives, preparation method and compositions containing same

Group B streptogramin derivatives of general formula (I):wherein Ra, Rb, Rc, Rd, R, Rand Y are as defined in the description, including preparation methods and compositions containing same. Such derivatives are particularly useful as antimicrobial agents, optionally combined with at least one group A streptogramin derivative.

Streptogramines, their preparation and compositions containing them

Devices and processes for synthesizing, purifying and analyzing large numbers of compounds for use in combinatorial libraries, are disclosed. The processes involve generating a series of compounds in multi-well plates or multi-tube racks, purifying the reaction mixtures, analyzing the purified compounds, and optionally performing bioassays on the compounds. The information regarding the compounds is stored in a central database. The devices include one or more multi-tube arrays, a purification device, means for transferring the contents of the tubes, a solvent evaporator, analytical instrumentation, and, optionally, a weighing instrument. The multi-tube array(s) optionally include a cover, which can be placed on or removed from the array by computer control. By correlating the orientation of tubes from one stage to the next, it is possible to use a single bar code or other identifying mark for each multi-tube array rather than for each individual tube. This simplifies data collection for large numbers of compounds.

Method and apparatus for synthesizing characterizing and assaying combinatorial libraries

A method of controlling parasites in or on an animal comprising orally administering to the animal a parasitically effective, substantially non-emetic 1-arylpyrazole.

Growing community of inventors

Raleigh, NC, United States of America

Yves Ribeill