Institut National De La Sante Et De La Recherche Medicale

Yves Courtois

Denis S Barritault

Michel Prunieras

Isabelle Guedon Born Saglier

Cristina Arruti

Yves Pouliquen

A process for stimulating the growth of epidermis cells. The epidermis cells are contacted with an aqueous saline extract (RE) of ocular tissues. The process is especially applied for human epidermis cells. Application to the study of chromosomes of the human epidermis cell, particularly for the detection of natural or induced chromosome anomalies, and to the production of grafts, and especially autografts, usable on man, for example in the treatment of burns, cosmetic and diagnostic products.

Cosmetic compositions containing retinal extracts for increasing

Process for stimulating the growth of epidermal cells

A composition and a method for regenerating wounded or damaged corneal epelium are described. The composition comprises an aqueous solution containing an effective amount of ocular extract RE. The RE is extracted from eye tissues, such as choroid, iris and vitreous as well as aqueous humor. The active extract is obtained by the treatment of bovine ocular tissues with a buffered aqueous saline solution at pH of about 7.2. For ophthalmological use, the RE extract is purified by precipitation with acetic acid and dialyzed against physiologic saline NaCl solution. Such a composition is shown to increase significantly the rate of healing of wounded corneal epithelium.

Method for regenerating corneal epithelium

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Gif sur Yvette, France

Yves Courtois