Societe De Conseils De Recherches Et D'applications Scientifiques (s.c.r.a.s.)

National Institute of Health and Medical Research

Durect Corporation

Societe De Conseils De Recherches Et D'applications Scientifiques

Yves Christen

Pierre Potier

Claude Thal

Catherine Guillou

Jean-Luc Puel

Remy Pujol

Dolor Renko

Aude Mary

The invention features methods and devices for local delivery of agents that modify glutamate-mediated neurotransmission to the inner ear for treatment of inner ear disorders caused by glutamate-induced hearing loss and/or tinnitus.

Delivery of modulators of glutamate-mediated neurotransmission to the inner ear

A method of treating sarcopenia in warm-blooded animals comprising administering to warm-blooded animals in need thereof an amount of an extract ofcomprising from 5.5 to 8% in total of ginkgolides A, B, C and J, from 40 to 60% of flavoneglycosides and from 5 to 7% of bilobalide sufficient to treat sarcopenia.

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The invention concerns the use ofextracts, and in particularextracts comprising 20 to 30% of flavoneglycosides, 2.5 to 4.5% in total of gingkolides A, B, C and J, 2 to 4% of bilobalide, less than 10% of proanthocyanidins and at least 10 ppm of alkylphenol type compounds, for preparing a medicine for treating sarcopenia.

The invention relates to the use of extracts of , and in particular extracts of comprising 20 to 30% of flavoneglycosides, 2.5 to 4.5% of ginkgolides A, B, C and J, 2 to 4% of bilobalide, less than 10% of proanthocyanidines and less than 10 ppm of compounds of alkylphenol type, for preparing a medicament intended to treat amyotrophic lateral sclerosis.

Use of ginkgo biloba extracts for preparing a medicine for treating amyotrophic lateral sclerosis

Galanthamine derivatives, and their pharmaceutical compositions

Growing community of inventors

Paris, France

Yves Christen