Pierre Fabre Medicament

Pierre Fabre Dermo-cosmetique

Pierre Fabre Dermot-cosmetique

Yves Brunel

Bernard Vacher

Stéphane Poigny

Nathalie Castex-Rizzi

Jean-Louis Maurel

Hélène Hernandez-Pigeon

Philippe Uriac

Marie Françoise Aries

Stëphane Poigny

Florence Castan-Cuisiat

Jacques Dubois

Estelle Marchal

The present invention relates to the novel combination of pongamia oil and 4-t-butylcyclohexanol, and to the uses thereof in the fields of cosmetics and dermatology to combat redness. More specifically, the present invention relates to the cosmetic use of a composition comprising said combination to combat rosacea.

Cosmetic composition comprising a combination of pongamia oil and 4-t-butylcyclohexanol for the treatment of rosacea

The present invention relates to methylene furanone derivatives as well as the use thereof as a protective, antioxidant, or depigmentation agent in cosmetic or dermatological compositions. The invention also relates to a method for preparing said derivatives involving a Suzuki-Miyaura coupling reaction from corresponding dibromofuranone derivatives. The invention also relates to a method of preparation involving a coupling reaction of 2-methoxy-furan derivatives with a ketone followed by dehydration.

Methylene furanone derivatives and use of said derivatives as a photoprotecting or antioxidant or depigmentation agent in cosmetic or dermatological compositions

The invention relates to a new process for the preparation of N-[3-[(2-methoxyphenyl)sulfanyl]-2-methylpropyl]-3,4-dihydro-2H-1,5-benzoxathiepin-3-amine.

Process for the synthesis of N-[3-[(2-methoxyphenyl] sulfanyl] -2-methylpropyl] -3,4-dihydro-2H-1,5-benzoxathiepin-3-amine

The invention relates to preparing derivatives of formula (1), wherein, in particular Rand R, identical or different, represent a hydrogen, flourine or chlorine atom, a hydroxy group, an alkyl radical and an alkoxy radical, Ris an alkyl radical, a hydroxy group, or a methoxy radical, Ris a hydrogen atom or a methyl radical and Rand R, identical or different, represent a hydrogen atom, an alkyl radical, an alkoxy radical, an alkylthio radical, and an alkylamino radical. The inventive method consists in reducing an amid of formula (9). 

Synthesising method and benzoxathiepine intermediates

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Marssac-sur-tarn, France

Yves Brunel