Medprin Regenerative Medical Technologies Co., Ltd.

Yuyu Yuan

Kunxue Deng

Tao Xu

Guangyao Li

Yaya Yang

Cheng Ma

Linjing Li

Limin Lin

Guoshuai Wang

Kuilin Lai

Zeyue Guo

Zefeng Zhan

A degradable and absorbable hemostatic fiber material, a preparation method therefor, and a hemostatic fiber article thereof. The carboxylation degree of the hemostatic fiber material is 10-25%, and the polymerization degree of the hemostatic fiber material is 10-250. The hemostatic fiber material comprises fiber filaments, the linear density of the fiber filament being 0.8-4.5 dtex, and the dry strength of the fiber filament being 10-150 cN/tex. The degradable and absorbable hemostatic fiber material has a higher carboxylation degree and a lower polymerization degree, while the strength and completeness of the fiber filament can be well maintained, such that the hemostatic effect is better and the hemostasis is faster. Further, the hemostatic fiber material can be degraded and absorbed, and thus is safer.

Degradable and absorbable hemostatic fiber material, preparation method therefor, and hemostatic fiber article thereof

A tissue repair fibrous membrane, preparation method and application thereof, and tissue repair product. The tissue repair fibrous membrane is formed by interweaving fiber filaments having a diameter of 10 nm to 100 &#x3bc;m, and has pore structures formed by interweaving between the fiber filaments. The fiber filaments have concave structures, and have annular convex structures thereon in the radial direction of the filaments.

Tissue repair fiber membrane, preparation method and application thereof, and tissue repair product

A medical hydrogel composition, a medical hydrogel, a preparation method therefore and an application thereof, and a medical hydrogel kit. The medical hydrogel composition comprises a first component and a second component; the first component comprises polylysine and polyethylene imine; the second component comprises one or more of 4-arm-polyethylene glycol-succinimidyl glutarate, 4-arm-polyethylene glycol-succinimidyl succinate, and 4-arm-polyethylene glycol-succinimidyl carbonate; the degree of polymerization of the polylysine is 20 or more. The medical hydrogel is formed by reacting the first component with the second component of the medical hydrogel composition. The medical hydrogel kit comprises the medical hydrogel composition and a buffer solution used for dissolving the components of the medical hydrogel composition. The medical hydrogel has a degree of swelling of &#x2212;10%-50%, and can be applied in narrow parts where cranial, spinal, and peripheral nerves are densely distributed.

Medical hydrogel composition, and medical hydrogel, preparation method therefor and application thereof

The present disclosure discloses reinforced electrospun fibrous membranes and preparation methods therefor. The reinforced electrospun fibrous membranes can include an electrospun fibrous membrane body and a plurality of reinforcing thread sets fixed to the electrospun fibrous membrane body through holes thereon, wherein any two of the plurality of reinforcing thread sets are parallel to each other; each of the reinforcing thread sets comprises a starting end and a terminal end, both being connected to an edge of the electrospun fibrous membrane body; each of the reinforcing thread sets comprises at least one reinforcing fibrous thread consisting of a main thread and an auxiliary thread respectively arranged at a front side and a bottom side of the electrospun fibrous membrane body and configured to interlace each other at the through hole. By providing reinforcing thread sets on the electrospun fibrous membrane body to impart the electrospun fibrous membrane with a greater mechanical property, the mechanical strength required for the movement of the tissue is ensured, and the electrospun fibrous membrane is easy to be folded or rolled into other shapes. The electrospun fibrous membrane body may be made of degradable materials, which are gradually degraded and absorbed in the process of inducing new tissue formation, thereby providing space for the formation of new tissues.

Reinforced electrospun fibrous membrane and preparation method thereof

Disclosed are an artificial dura mater and manufacturing method thereof. The artificial dura mater includes electrospun layers prepared by electrostatic spinning, at least one of which is a hydrophobic electrospun layer. Further, above the hydrophobic electrospun layer, there can be at least one hydrophilic electrospun layer. A transition layer can be further included between the hydrophobic and the hydrophilic electrospun layers. Additionally, cytokines and/or medicines can be affixed to either or both of the hydrophobic and the hydrophilic electrospun layers, by way of bio-printing. The disclosed artificial dura mater shows good biocompatibility, enhances dural tissue regeneration, achieves excellent repairing effects, prevents adhesion, allows complete absorption, has good mechanical properties, ensures low infection rates, and can be loaded with therapeutic agents.

Artificial dura mater and manufacturing method thereof

Method for treating defective dura mater

Treating defective dura with synthetic artificial dura substitute

Growing community of inventors

Guangdong, China

Yuyu Yuan