Yamaguchi University

Eiken Kagaku Kabushiki Kaisha

Yutaka Suehiro

Tomomi Hoshida

Takahiro Yamasaki

Kohsuke Sasaki

Yuji Hinoda

Takae Okada

A feces collection sheet (S), which has a cylindrical shape and includes: an upper sheet () having a feces receiving portion () in a center of the upper sheet (); and a lower sheet (), which is provided so as to extend from both of a right-side edge portion and a left-side edge portion of the upper sheet () and is configured to define a gap with the upper sheet () to allow insertion of a toilet seat therethrough. The upper sheet () and the lower sheet () are made of a material having a water-soluble material property. The upper sheet () has a folded piece portion () adapted to be unfolded to enable the feces receiving portion () to form a three-dimensional shape that bulges toward the lower sheet ().

Feces sampling sheet

The present invention aims to provide a method for determining breast cancer susceptibility, in which a DNA copy number polymorphism associated with breast cancer susceptibility is identified and determination is made based on an increase or decrease in the DNA copy number polymorphism. The present invention attempts to achieve this by performing microarray assay using the peripheral blood of sporadic breast cancer patients, identifying a DNA copy number polymorphism associated with breast cancer susceptibility in a chromosomal region, detecting the number of copies of the above DNA copy number polymorphism by quantitative PCR, and then determining breast cancer susceptibility based on an increase or decrease in the DNA copy number polymorphism. Furthermore, the precision of the determination of breast cancer susceptibility can be improved by detecting a DNA copy number polymorphism by the aforementioned quantitative PCR by selecting two or more chromosomal regions and then performing a discriminant analysis based on the results thus obtained.

Method for assessing breast cancer susceptibility

Growing community of inventors

Yamaguchi, Japan

Yutaka Suehiro