Yamanouchi Pharmaceutical Company Ltd.

Yutaka Konno

Hiroitsu Kawata

Masayoshi Aruga

Takashi Sonobe

Mitsuo Mitomi

Yukio Kubota

Tadayoshi Ohmura

Muneo Fukui

Shunji Hasumi

Toshimitsu Konno

Shumpei Yamaguchi

Ken Iwai

Shigeo Kawamura

Seiki Tashiro

A patch having good transdermal property which utilizes a suppository base e.g. triglyceride of a vegetable saturated fatty acid having 12 to 18 carbon atoms together with a penetration enhancer.

Patch

A novel plaster structural assembly is provided for iontophoresis wherein th e assembly is comprised of an electrode layer and a medicament-containing layer in which a water supplying layer is disposed between the electrode layer and the medicament-containing layer with a sealing cover disposed on the outside of the electrode layer. A method for using the structural assembly for iontophoresis is also provided.

Plaster structural assembly for iontophoresis

A formulation is provided for the transdermal administration of nicardipine hydrochloride. The formulation is comprised of nicardipine hydrochloride dissolved or suspended in a mixed liquid composed of an urea and at least one compound selected from the group consisting of propylene glycol, a monohydric alcohol having 2 to 4 carbon atoms, lactic acid, thioglycol, a middle chain fatty acid glyceride and a sorbitan middle chain fatty acid ester compounded with a transdermal formulation base.

Transdermal formulation of nicardipine hydrochloride

An oily composition of an antitumor drug comprising at least one sparingly oil soluble or water-soluble antitumor drug, at least one fat or oil, and at least one solubilizing adjuvant in an oily vehicle selected from the group consisting of crown ether, lecithin, polyethylene glycol, propylene glycol, vitamin E, polyoxyethylene alkylether, and sucrose esters of fatty acids.

Oily compositions of antitumor drugs

A solid microdose drug preparation containing a microdose drug such as formoterol fumarate or .beta.-methyldigoxin coated with wax. In the drug preparation, the stability and the content uniformity of the microdose drug have been improved.

Solid drug preparations

A stable suppository useful as an antiasthmatic agent containing 3-formylamino-4-hydroxy-.alpha.-[N-(1-methyl-2-p-methoxyphenylethyl)aminom ethyl]benzyl alcohol.1/2fumarate monohydrate, polyvinyl pyrrolidone, and at least one of cyclodextrin, dextran and magnesium metasilicate aluminate together with a suppository base.

Growing community of inventors

Saitama, Japan

Yutaka Konno