Kao Corporation

Kao Corporaion

Yusuke Shibuya

Ryuji Ochiai

Akihiko Fujii

Hideo Oominami

Atsushi Suzuki

Shigeru Moriwaki

Naoko Tsuji

Mitsuyoshi Sakasai

Azumi Nagasawa

Yoshie Yamasaki

An NFAT signal inhibitor and the like are provided. An NFAT signal inhibitor and the like, containing, as an active ingredient, at least one compound selected from the group consisting of a coumarin derivative represented by formula [where in the formula (I), Rand R, which may be identical with or different from each other, each represent a hydrogen atom or a group represented by formula (II) (where in the formula (II), Rrepresents a linear or branched alkyl or alkenyl group having 1 to 20 carbon atoms)] and pharmacologically acceptable salts thereof.

NFAT signal inhibitor and hair-growing agent

Provided are a water-soluble ginger root extract which is a water extract or a hydrous alcohol extract of a ginger root and is substantially free of gingerols; and a hair growth inhibitor and a preparation for external use each containing the extract. The water-soluble ginger root extract of the present invention causes less skin irritation because of being substantially free of gingerols, and has excellent body-hair growth inhibiting effects, so that it is useful as a hair grown inhibitor and a preparation for external use, each having a high degree of safety.

Water-soluble ginger root extract

Provided is a coffee composition which does not generate hydrogen peroxide in the body even if it is taken for long periods of time. The coffee composition has a hydroxyhydroquinone content of 0 to 0.00005 wt. %.

Coffee drink composition

Provided is a coffee composition having an excellent hypotensive effect. The coffee composition has the following components (A) and (B):

Growing community of inventors

Haga-gun, Japan

Yusuke Shibuya