Nissan Chemical Industries Limited

Yusuke Inaba

Yuichi Hirai

Michiaki Adachi

Noriko Saito

Hiroshi Nagai

Yusuke Shintani

Takeshi Kawazu

Koichi Yasutake

Megumi Ueno

Daiki Takahashi

Jun Egi

There is provided a novel triazinone compound that has an excellent T-type voltage-dependent calcium channel inhibitory activity and is specifically useful for treatment of pain. A compound of Formula (I), a tautomer of the compound, a pharmaceutically acceptable salt thereof, or a solvate thereof: where each substituent is defined in detail in the description or claims, for example Ris H or Calkoxy, etc., each of Land Lis independently a single bond or NR, etc., Lis Calkylene, etc., A is Caryl or 5 to 10-membered heteroaryl which is optionally substituted, etc., B is Ccycloalkylene, etc., D is Caryl or 5 to 10-membered heteroaryl which is optionally substituted, etc.

Triazinone compound and T-type calcium channel inhibitor

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Funabashi, Japan

Yusuke Inaba