Asahi Kasei Microdevices Corporation

Banyu Pharmaceutical Co. Ltd

Nippon Denko Co., Ltd

Yusuke Hidaka

Takeshi Watanabe

Osamu Shirata

Masahiko Kobayashi

Ken-ichi Tanaka

Hiraku Itadani

Takao Nakamura

Tetsuo Takimura

Masataka Ohta

Kenji Niiyama

Yoshiaki Iida

Masaaki Hosoi

Tomoharu Itoh

Hiroshi Takeshita

Kenji Okamoto

Yoshio Hioki

Ryo Nishioka

Hiroki Uede

Masasuke Yamaba

Semiconductor module

To achieve a size reduction of a semiconductor package while securing stability in mounting. Three terminals t, t, and tare individually arranged on a semiconductor packagehaving a rectangular shape as viewed in plan in such a manner that the center in the longitudinal direction of the semiconductor packageof each of the three terminals t, t, and tand the center in the longitudinal direction of each of the other terminals are not overlapped with each other as viewed from the side of the long side. The terminal tand the other terminals tand tare arranged in such a manner that the terminal tand the other terminals tand tare present on mutually different sides across a line segment M passing through the center in the width direction, an angle θ formed by two line segments connecting the center of gravity of the terminal t, the position in the longitudinal direction of which is the center, and the center of gravity of each of the other terminals tand tis 60° or more, and a width Lof the semiconductor packageand a distance Lt between the rightmost end position of the terminal tarranged at the rightmost end in the width direction of the semiconductor packageand the leftmost end position of the terminal tor tarranged at the leftmost position in the width direction satisfy Lt/L≥0.5.

Semiconductor package and camera module

To achieve a size reduction of a semiconductor package while securing stability in mounting. Three terminals t, t, and tare individually arranged on a semiconductor packagehaving a rectangular shape as viewed in plan in such a manner that the center in the longitudinal direction of the semiconductor packageof each of the three terminals t, t, and tand the center in the longitudinal direction of each of the other terminals are not overlapped with each other as viewed from the side of the long side. The terminal tand the other terminals tand tare arranged in such a manner that the terminal tand the other terminals tand tare present on mutually different sides across a line segment M passing through the center in the width direction, an angle &#x3b8; formed by two line segments connecting the center of gravity of the terminal t, the position in the longitudinal direction of which is the center, and the center of gravity of each of the other terminals tand tis 60&#xb0; or more, and a width Lof the semiconductor packageand a distance Lt between the rightmost end position of the terminal tarranged at the rightmost end in the width direction of the semiconductor packageand the leftmost end position of the terminal tor tarranged at the leftmost position in the width direction satisfy Lt/L1&#x2265;0.5.

A ceria-zirconia-based composite oxide oxygen storage material with a fast oxygen storage rate having an OSC ability enabling fast response to changes in exhaust gas which does not greatly fluctuate in composition, but varies at a fast rate near the stoichiometric air-fuel ratio, an exhaust gas purification catalyst, and a honeycomb structure for exhaust gas purification are provided. A ceria-zirconia-based composite oxide oxygen storage material, which oxygen storage material has a molar ratio of cerium and zirconium, by cerium/(cerium+zirconium), of 0.33 to 0.90, has an ion conductivity measured by an AC impedance method of 1&#xd7;10S/cm or more at 400&#xb0; C., and contains metal ions M of one or more types of rare earth elements selected from Sm, Eu, Pr, Gd, and Dywith a coordination number of over 7.0 in an amount of 0.5 mol % to 15 mol % with respect to the total amount of cations.

Ceria-zirconia-based composite oxide oxygen storage material, exhaust gas cleaning catalyst, and honeycomb structure for exhaust gas cleaning

To achieve a size reduction of a semiconductor package while securing stability in mounting. Three terminals t, t, and tare individually arranged on a semiconductor packagehaving a rectangular shape as viewed in plan in such a manner that the center in the longitudinal direction of the semiconductor packageof each of the three terminals t, t, and tand the center in the longitudinal direction of each of the other terminals are not overlapped with each other as viewed from the side of the long side. The terminal tand the other terminals tand tare arranged in such a manner that the terminal tand the other terminals tand tare present on mutually different sides across a line segment M passing through the center in the width direction, an angle &#x3b8; formed by two line segments connecting the center of gravity of the terminal t, the position in the longitudinal direction of which is the center, and the center of gravity of each of the other terminals tand tis 60&#xb0; or more, and a width Lof the semiconductor packageand a distance Lt between the rightmost end position of the terminal tarranged at the rightmost end in the width direction of the semiconductor packageand the leftmost end position of the terminal tor tarranged at the leftmost position in the width direction satisfy Lt/L&#x2264;0.5.

A full-length cDNA encoding a human-derived G protein-coupled receptor protein is isolated by screening a human hippocampus library. Also, a rat-derived cDNA corresponding to the human-derived cDNA is isolated. Proteins encoded by these cDNAs have an activity of lowering intracellular cAMP concentration under stimulation with histamine. These proteins are usable as tools in screening ligands thereof or in screening candidate compounds for drugs capable of regulating signal transduction from the above proteins.

Guanosine triphosphate (GTP) binding protein-coupled receptor proteins that bind histamine and are expressed in the brain

Guanosine triphosphate (GTP) binding protein-coupled receptor proteins

The present invention has provided a human-derived novel G protein-coupled receptor protein expressed in the brain, rat-derived protein corresponding to it, and their genes. Use of the receptors makes it possible to screen their ligands and compounds that are candidates for medicines. These ligands and candidate compounds would be useful in the diagnosis and treatment of diseases arising from disorders of signal transduction pathway mediated by the G protein-coupled receptor of the invention.

A substituted pyridine derivative represented by the general formula ##STR1## wherein R.sup.1 represents a phenyl or naphthyl group which may optionally be substituted by a substituent selected from the class consisting of a hydroxyl group, lower alkyl groups, lower alkoxy groups, cycloalkyl groups, lower alkoxycarbonyl groups, a phenyl group and halogen atoms; X represents an oxygen atom, a sulfur atom, a carbonyl group, or a group of the formula --CH(OH)-- or --N(R.sup.a)-- in which R.sup.a is a hydrogen atom or a lower alkyl group; Y represents a linear or branched lower alkylene group or a vinylene group which may optionally be substituted by a lower alkyl group, with the proviso that when X is an oxygen or sulfur atom, Y represents the lower alkylene group; R.sup.2 and R.sup.3 are identical or different and each represents a hydrogen atom or a lower alkyl group; R.sup.4 represents a hydrogen atom, a lower alkoxy group, a cycloalkyloxy group, a lower alkylthio group, a cycloalkylthio group, an aryloxy group, an aralkyloxy groups or a group of the formula ##STR2## in which R.sup.b and R.sup.c are identical or different and each represents a hydrogen atom or a lower alkyl group. or R.sup.b and R.sup.c, taken together, may form together with the adjacent nitrogen atom a 5- to 7-membered saturated heterocyclic ring which may optionally contain at least one additional hetero atom selected from the group consisting of oxygen, sulfur and nitrogen atoms and may optionally be substituted by a lower alkyl group; m and n are each 0 or 1, with the proviso that m and n are not 0 at the same time, or an acid addition salt thereof. This compound is useful as an antiulcer agent.

Anti-ulcer substituted pyridine derivatives

Growing community of inventors

Tokyo, Japan

Yusuke Hidaka