The University of Akron

Yusheng Chen

Matthew L Becker

James A Wilson

An end and monomer functionalized poly(propylene fumarate) polymer and methods for preparing this polymer, comprising isomerized residue of a maleic anhydride monomer and a functionalized propylene oxide monomer according to the formula:  where n is an integer from more than 1 to 100; R is the residue of an initiating alcohol having a propargyl, norbornene, ketone or benzyl functional group; and R' is a second functional group selected from the group consisting of propargyl groups, 2-nitrophenyl groups, and combinations thereof are disclosed. The end and monomer functional groups allow for post-polymerization modification with bioactive materials using 'click' chemistries and use of the polymer for a variety of applications in medical fields, including, for example, 3-D printed polymer scaffold.

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Akron, OH, United States of America

Yusheng Chen