Showa Denko K.k.

Showa Denko Kabushiki Kaisha

Yuseki Suyama

Motoo Miura

Yoshimasa Ishimura

Kouhei Morikawa

Kohei Morikawa

Kuniomi Marumo

Taketoshi Naito

Hiroyuki Monzen

Tsutomu Nozawa

Shuuji Hirayama

Nobuyuki Nagato

Masatoshi Murakami

Takami Oe

The invention intends to provide means for producing halogenated aromatic methylamine useful as an intermediate in the production of agrochemical or medical preparations, by an industrially advantageous method. The process according to the present invention for producing halogenated aromatic methylamine is characterized by comprising hydrogen-reducing a halogenated aromatic nitrile represented by formula (1):(wherein X represents a chlorine atom or a fluorine atom, m represents an integer of 1 to 5, n represents an integer of 1 to 5, m+n&#x2266;6, and when n is 2 or more, each X may be the same or different) using a hydrogenating catalyst in the presence of an organic acid in a solvent to produce a halogenated aromatic methylamine represented by formula (2):(wherein X, m and n have the same meanings as defined above, and a represents an integer of 1 to m).

Production process for halogenated aromatic methylamine

To provide a novel method for producing a fluorinated benzenedimethanol compound useful as a starting material or an intermediate in the production of agricultural or medicinal chemicals in an industrially advantageous manner. A method for producing a fluorinated benzenedimethanol compound according to the present invention comprises the steps of reducing the nitrile groups of a fluorinated benzenedinitrile compound to obtain a fluorinated xylylenediamine compound and then converting the aminomethyl groups of the fluorinated xylylenediamine compound into hydroxymethyl groups.

Production method for benzenedimethanol compound

An object of the present invention is to provide a process for producing a fluorinated methyl-benzyl alcohol, which process is industrially applicable. A process for producing a fluorinated methyl-benzyl alcohol according to the present invention includes hydrogenolysis of one hydroxyl group in fluorinated benzene dimethanol. The hydrogenolysis can be carried out in a solvent in the presence of a catalyst. The catalyst can include at least one metal selected from cobalt, iron, copper, nickel, platinum, palladium, and rhenium, and the hydrogenolysis can be carried out using hydrogen.

Process for producing fluorinated methyl-benzyl alcohol

Noble metal, particularly ruthenium, Raney catalysts which can hydrogenate (1) aromaticity-exhibiting ring portions of organic compounds, (2) carboxylic acids and their ester portions (carbonyl ester groups), (3) ring portions and carboxylic acid or their ester groups in compounds having such ring portions and carboxylic acid or their ester portions, and (4) ring portions and nitrile groups of aromatic nitrile compounds and methods for the preparation of corresponding hydrogenated compounds. The methods allow preparation of hydrogenated compounds having hydrogenated aromatic ring portions, hydrogenated carbonyl ester groups, hydrogenated aromatic ring and carbonyl ester groups, or hydrogenated aromatic rings and nitrile groups under milder hydrogen pressure and temperature conditions than the conventional catalysts.

Metal raney catalysts and preparation of hydrogenated compounds therewith

Noble metal raney catalysts and preparation of hydrogenated compounds therewith

Process for preparing cyano group-containing aromatic methylamines

Noble metal, particularly ruthenium, Raney catalysts having the property of catalyzing the hydrogenation of (1) aromaticity-exhibiting ring portions of organic compounds, (2) carboxylic acids and their ester portions (carbonyl ester groups), (3) ring portions and carboxylic acid or their ester groups in compounds having such ring portions and carboxylic acid or their ester portions, and (4) ring portions and nitrile groups of aromatic nitrile compounds and methods for the preparation of corresponding hydrogenated compounds. The methods allow preparation of hydrogenated compounds having hydrogenated aromatic ring portions, hydrogenated carbonyl ester groups, hydrogenated aromatic ring and carbonyl ester groups, or hydrogenated aromatic rings and nitrile groups under milder hydrogen pressure and temperature conditions than the conventional catalysts.

Noble metal Raney catalysts and preparation of hydrogenated compounds

An allyl type amine is prepared by reacting an allyl type alcohol represented by the following formula: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 independently stand for a hydrogen atom, an aliphatic hydrocarbon group or alicyclic hydrocarbon having 1 to 8 carbon atoms, or an aromatic hydrocarbon group, with at least one member selected from the group consisting of ammonia, a primary amine and a secondary amine in the presence of a palladium compound and a multidentate phosphorus compound.

Growing community of inventors

Kawasaki, Japan

Yuseki Suyama