Spiber Inc.

Riken Corporation

Yunosuke Abe

Keisuke Morita

Shota Togashi

Junichi Sugahara

Keiji Numata

Tetsuo Asakura

Ayumi Abe

Takehisa Maekawa

Hiroyuki Nakamura

Kenji Kurachi

Masato Matsuo

Koichi Kotaka

Hirotada Ando

The present invention relates to a modified fibroin including a domain sequence represented by Formula 1: [(A)motif-REP]or Formula 2: [(A)motif-REP]-(A)motif, and having a serine residue content rate of less than 5.5%. [In Formula 1 and Formula 2, the (A)motif represents an amino acid sequence consisting of 4 to 27 amino acid residues, and the number of alanine residues with respect to the total number of amino acid residues in the (A)motif is 80% or more. REP represents an amino acid sequence consisting of 10 to 200 amino acid residues. m represents an integer of 10 to 300. The plurality of (A)motifs may be the same amino acid sequence or different amino acid sequences. A plurality of REPs may be the same amino acid sequence or different amino acid sequences.]

Modified fibroin

The present invention provides a modified fibroin fiber having a shrinkage history of being irreversibly shrunk after spinning, the modified fibroin fiber containing modified fibroin, wherein a fiber diameter of a raw material fiber before being irreversibly shrunk exceeds 25 μm.

Modified fibroin fibers

The present invention relates to a polypeptide solution in which a polypeptide including an amino acid sequence derived from type I keratin that belongs to Cluster Ia is dissolved in a solvent including a formic acid or a solvent including an aprotic polar agent having a dipole moment of 3.0 D or more and an inorganic salt.

Polypeptide solution, production method for polypeptide fiber, and artificial polypeptide

The present invention relates to a modified fibroin including a domain sequence represented by Formula 1: [(A)motif-REP]or Formula 2: [(A)motif-REP]&#x2212;(A)motif, in which the domain sequence has an amino acid sequence with a reduced content of a glutamine residue equivalent to an amino acid in which one or a plurality of glutamine residues in REP are deleted or substituted with other amino acid residues, as compared with a naturally occurring fibroin.

Growing community of inventors

Tsuruoka, Japan

Yunosuke Abe