The Royal Institution for the Advancement of Learning / Mcgill University

Ontera Inc.

Nooma Bio, Inc.

Yuning Zhang

William Dunbar

Xu Liu

Peter Grutter

Walter Reisner

Yoichi Miyahara

The apparatus for making a nanopore in a membrane generally has an electrode configured to connect to one of two opposing surfaces of the membrane; a conductive tip configured to contact a location of the other one of the two opposing surfaces of the membrane; and a voltage source electrically connected between the electrode and the conductive tip and operable to generate an electric potential across the membrane, the electric potential locally removing material of the membrane at the location to make the nanopore.

Method and apparatus for making a nanopore in a membrane using an electric field applied via a conductive tip

Described herein are nanopore devices as well as methods for assembling a nanopore device including one or more nanopores that can be used to detect molecules such as nucleic acids, amino acids (proteins), and the like. Specifically, a nanopore device includes an insulating layer that reduces electrical noise and thereby improves the sensing resolution of the one or more nanopores integrated within the nanopore device.

Wafer-scale assembly of insulator-membrane-insulator devices for nanopore sensing

Growing community of inventors

Montreal, Canada

Yuning Zhang