Shandong Huaan Biotechnology Co., Ltd.

Yipurun (shanghai) Biotechnology Co., Ltd.

Yunhong Mu

Bin Huang

Zheng Long Wei

Wei Yan

Jian Xie

Peipei Xia

Xiuli Wang

Zheng Wei

The present invention relates to a degradable vascular stent capable of avoiding late restenosis, comprising a base region formed by a polylactic acid based polymer; at least one storage region in which an active agent is stored; and an outer layer of a drug sustained release coating covered on the base region and/or the storage region. Before the mass of the polylactic acid based polymer is decreased by 10-20%, the active agent is retained in structural units of the polylactic acid based polymer. After the mass of the polylactic acid based polymer is decreased by 10-20%, the active agent is released from the storage region. The base region provides a supporting capacity for ensuring patency of blood vessels; the drug sustained release coating is used for drug release in an early stage; and the active agent only works in late degradation of the stent to avoid late restenosis.

Degradable vascular stent capable of avoiding late restenosis

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Shanghai, China

Yunhong Mu