Shanxi Zhendong Pilot Biological Science and Technology Co., Ltd.

Yunheng Shen

Weidong Zhang

Juan Su

Runhui Liu

Lei Shan

Huiliang Li

Xike Xu

Huizi Jin

Preparation and application of line leafflower lactone A for treating myocarditis having a structure of The compound shows positive therapeutic activity against Coxsackie virus and significant dose dependent correlation. The line leafflower lactone A prevents disease in mouse models of experimental autoimmune myocarditis and onset of the process by intraperitoneal injection of a dose of 20 mg/kg/d. When increased to 100 mg/kg/d, the line leafflower lactone A shows positive therapeutic effect on EAM. Line leafflower lactone A is used as the sole active ingredient and combined with a conventional pharmaceutical carrier in a drug for treating myocarditis, and the pharmaceutical composition may be in the form of tablets, dispersible tablets, mouth collapse tablets, retard tablets, capsule, soft capsule, dropping pill, granules, injection, powder injection, or aerosol.

Line leaf inula flower lactone A and methods for preparing and using the same for treating myocarditis

Preparation and application of line leafflower lactone A in the multiple sclerosis, having a structure of  Line leafflower lactone A has therapeutic effects on experimental autoimmune encephalomyelitis (EAE) model, and is used to develop drug for treating multiple sclerosis (MS). Line leafflower lactone A drug is a combination containing the active ingredient of line leafflower lactone A and conventional pharmaceutically carrier, and may be in forms of tablets, dispersible tablets, mouth collapse tablets, retard tablets, capsule, soft capsule, dropping pill, granules, injection, powder injection, or aerosol. The pharmaceutical composition is used for treating multiple sclerosis, has tremendous developing potentiality because of its high value of clinical application.

Line leaf inula flower lactone A and methods for preparing and using the same for treating multiple sclerosis

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Shanghai, China

Yunheng Shen