Postech Academy-industry Foundation

Posco

Posco Co., Ltd

Yun Kee Jo

Hyung Joon Cha

Bong-Hyuk Choi

Yeonsu Jeong

Changsup Kim

Hogyun Cheong

An antimicrobial adhesive protein, an antimicrobial nanoparticle, an antimicrobial composition comprising the same nanoparticle, and a preparation method for the same composition are described and, more particularly, an antimicrobial adhesive protein in which an antibiotic peptide is linked to a mussel adhesive protein, a mussel adhesive protein derivative of which a tyrosine residue within the antimicrobial adhesive protein is modified with a catechol derivative, an antimicrobial nanoparticle including a metal capable of forming a coordinate bond with a derivative of the mussel adhesive protein and having intrinsic antimicrobial activity, an antimicrobial composition comprising the same nanoparticle, and a preparation method for the same composition are described.

Antimicrobial adhesive protein, antimicrobial nanoparticle, antimicrobial composition comprising same nanoparticle, and preparation method for same composition

The present invention relates to a fusion protein comprising a mussel adhesive protein and a silica-binding peptide linked to the mussel adhesive protein, a silica nanoparticle a silica connected to the fusion protein, a fusion protein-silica nanoparticle complex comprising the silica nanoparticle having bioactivity and adhesiveness for cell proliferation and accelerating the differentiation, a surface coating composition including the complex, its use, and a method of coating a surface using the surface coating composition.

Mussel-inspired bioactive surface coating composition generating silica nanoparticles

Growing community of inventors

Pohang-si, South Korea

Yun Kee Jo