Sunshine Lake Pharma Co., Ltd.

Yumei Tan

Yingjun Zhang

Qingyun Ren

Jiancun Zhang

Hongming Xie

Huichao Luo

Tianzhu Yu

Provided herein is a compound having Formula (I), or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a hydrate, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, which can be used for treating HCV infection or a HCV disorder. Also provided herein are pharmaceutical compositions comprising the compounds disclosed herein, which can be used for treating HCV infection or a HCV disorder. 

Bridged ring compounds as hepatitis C virus (HCV) inhibitors and pharmaceutical applications thereof

Disclosed are spiro compounds of formula (I), or stereomers, geometric isomers, tautomers, nitrogen oxides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or prodrugs thereof. The compounds can be used to treat hepatitis C virus (HCV) infection or hepatitis C disease. Furthermore disclosed are pharmaceutical compositions containing the compounds and the method of using the compounds or pharmaceutical compositions in the treatment of HCV infection or hepatitis C disease. 

Spiro compounds as Hepatitis C virus inhibitors

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Dongguan, China

Yumei Tan