Fuji Photo Film Company, Limited

Hitachi, Ltd.

Fujifilm Corporation

Heska Corporation

Fujirebio Inc.

Fujirebio Kabushiki Kaisha

Fujirejiro Inc.

Yukio Sudo

Osamu Seshimoto

Yoshihiro Ashihara

Nobuhito Masuda

Hiroshi Shinoki

Tetsuji Tanimoto

Toshikage Hiraoka

Yoshihiko Makino

Tadaharu Yokota

Masakazu Kurata

Masayoshi Kojima

Yoshiki Sakaino

Michiya Hiramoto

Shigeki Kageyama

Isao Nishizono

Hiroko Inomata

Makoto Yamakado

Junichi Yamanouchi

Toshihiro Mori

Keiichi Suzuki

Toshiaki Kubo

Hideyuki Karaki

Junji Nishigaki

Junichi Tamamoto

Isamu Tsubono

Akira Wakabayashi

Manabu Ogawa

Jean-Pierre Kinet

Tooru Takahashi

Tomoko Tashiro

Tadashi Ninomiya

Kenji Miura

Yuan Liu

Naofumi Hora

Y-s Edmond Cheng

Marie-Helene Jouvin

Bo Yang

Xiuqi Qian

John Chu

Tatsuo Kawabuchi

Revolving rollers, each provided on an outer peripheral surface thereof with revolving roller grooves extending therearound, are caused to mesh with a rack rod thread of a central rack rod with an axial angle over a lead angle of the rack rod thread and arranged for rotation on a holder member to be twisted. The holder member is rotated round the rack rod by a motor to translate the rack rod. A large thrust can be generated while ensuring a high reliability since a high efficiency is achieved by realizing rolling contact in set points of mesh of the rack rod thread and the revolving roller grooves, points of mesh are made planar, and interference in other points than the points of mesh can be suppressed. Also, play can be restricted by assembling the revolving rollers to the rack rod thread while applying torque in a direction, in which the axial angle is increased.

Mechanism for converting rotary motion into linear motion

An object of the present invention is to provide a microchip whereby, when chemical analysis is conducted, a specimen liquid can be directly collected and weighed without using any collecting and weighing devices. The present invention provides a microchip for analyzing liquid samples, which has a measuring structure for weighing and collecting a given amount of a specimen liquid within a range of 0.05 to 10 &#x3bc;l from an excessive amount of the specimen liquid which was introduced in the chip, wherein the measuring structure is located at the upstream side of an analysis element for analyzing a target substance in the specimen liquid inside the microchip.

Microchip and analysis method using the same

A liquid filtering instrumentaccording to the present invention achieves filtered liquid by pressure-reduced filtration, and it comprises a filter memberin which a liquid filteris accommodated, and a holder memberfor stocking filtered liquid passed through the liquid filter, wherein the filter memberand the holder memberare formed in capable of being fitted so as to be kept substantially air-tight and water-tight under pressure reduced state.

Liquid filtering instrument and dry type analysis device

According to the present invention, there is provided a fluorescent nucleotide represented by the formula: A-B-C, wherein A represents a residue of natural or synthetic nucleotide, oligonucleotide, polynucleotide, or derivative thereof, and binds to B at a base moiety in said residue; B represents a divalent linking group or a single bond; and C represents a monovalent group derived from a fluorescent dye having 0 or 1 sulfonic acid group or phosphoric acid group in a molecule. The present invention provides useful fluorescent nucleotides for labeling nucleic acids, specifically, fluorescent nucleotides of which uptake ratio is high in synthetic reaction of nucleic acids.

Fluorescent nucleotides

A power steering system for a vehicle. The system includes a hydraulic power cylinder, first and second hydraulic lines, a bypass passage through which the first and second hydraulic lines are connected with each other, and a flow passage change-over device adapted to close the bypass passage during steering assisting. A supply passage and a return passage are disposed in parallel with each other to form part of each of the first and second hydraulic lines. The flow passage change-over device is disposed in each of the first and second hydraulic lines. A differential pressure regulating valve is disposed in each of the return passages and adapted to allow hydraulic fluid to flow toward the hydraulic pressure source in a condition where pressure on side of the hydraulic power cylinder becomes higher than a set pressure or higher than pressure on side of the hydraulic pressure source.

Power steering system

An object of the present invention is to provide a method for detecting a protein using a nonradioactive label which is prevented to a smaller extent than in the case of the interaction of biotin/(strepto)avidin, and which achieves higher detection sensitivity than that of the detection system using DIG. The present invention provides a method for detecting a target substance, which comprises steps of: (A) allowing a target substance to come into contact with a protein labeled with a compound having a 6-membered ring, so as to carry out a binding reaction; and (B) detecting the protein labeled with the compound having a 6-membered ring, which was bound to the target substance, by using an antibody against the above compound having a 6-membered ring.

Method for detecting protein

The object of the present invention is to provide a method for analyzing double stranded DNA directly without denaturation. According to the present invention, there is provided a method of analyzing double stranded DNA present in an analyte, which comprises the steps of:

Method of analyzing double stranded DNA

A power steering system for a vehicle, comprises a steering shaft connected to a steering mechanism. A hydraulic power cylinder is provided for assisting a steering effort of the steering mechanism. A reversible pump is provided having first and second discharge ports which are respectively connected through first and second hydraulic lines with two hydraulic pressure chambers of the hydraulic power cylinder so that the two hydraulic pressure chambers are respectively provided with hydraulic pressures. A driving device is provided for driving the reversible pump to rightly and reversely rotate. A differential pressure regulating valve is disposed in the hydraulic circuit to maintain pressure at least in the first and second hydraulic lines at a level of atmospheric pressure or higher in an inoperative condition of the reversible pump.

A DNA chip or its analogue composed of nucleotide derivatives attached to a solid carrier is prepared by method of bringing nucleotide derivatives having a reactive group at each one terminal into contact with a solid carrier having thereon reactive groups in an aqueous phase in the presence of a transferase which is capable of producing a covalent bond by rearrangement of the reactive group of the nucleotide derivative and the reactive group of the solid carrier.

Fixation of nucleotide derivatives to solid carrier

Fluorescent substances

Disclosed are chemical agents with unexpected activity to inhibit the interactions between human immunoglobulin E (IgE) and its receptor (Fc.epsilon.RI) which interactions are known to be involved in triggering allergic responses. The agents may be used to module the allergic response in the treatment of various clinical conditions, including rhinitis, asthma, urticaria, atopic dermatitis, and anaphylacric shock. The agents can be formulated for oral, topical or parenteral administration.

Inhibition of the binding human IgE to its receptor by tetracyclic

A dry-type analytical element for immunoassay utilizing antigen-antibody reaction in which the antigenic component is isolated from the antibody component by incorporating both components in separate layers or separately in a layer using different solvents. The analytical element is excellent in sensitivity and accuracy, and the analytical operation is simple.

Analytical element for immunoassay and method for its preparation

A dry-type analytical element for immunoassay having at least one water-permeable layer for measuring a ligand in a sample according to enzyme immunoassay, which comprises,

Dry-type analytical element for immunoassay

An immunoassay element for quantitatively analyzing a ligand by determining the change in enzymatic activity caused by a reaction between the ligand, a linked product of the ligand and a high molecular weight compound and an enzyme-labelled antibody. The immunoassay element comprises a substrate layer containing a non-diffusible substrate which forms a diffusible material in the presence of the enzyme, and a reagent layer containing a fragmenting enzyme for further fragmenting the non-difussible material. Also provided is a process for quantitatively analyzing a ligand contained in a sample by the use of the immunoassay element.

Immunoassay element and process and immunoassay

A method of preparing a dry-type analytical element for immunoassay having at least one water-permeable porous layer and containing a labeled antigen and an antibody to said labeled antigen and to an unlabeled antigen as the components participating in antigen-antibody reaction in said porous layer, which comprises applying or impregnating a first composition containing one of said labeled antigen and said antibody and thereafter applying or impregnating a second composition containing the other of said labeled antigen and said antibody dissolved or suspended in a solvent not dissolving substantially said labeled antigen or said antibody in the first composition onto said porous layer.

Method of preparing immunological analytical element

Growing community of inventors

Saitama, Japan

Yukio Sudo