Ajinomoto Co., Ltd.

Yukio Nihei

Kazuo Ohishi

Manabu Suzuki

Akira Okano

Yoshihiro Morinaga

Yasuyo Suga

Toshihiro Hatanaka

Hideyuki Tanaka

Nobuyasu Suzuki

Takashi Tsuji

Takayuki Tanaka

Toshihiko Ando

Koji Ohsumi

Eiji Nakanishi

Nobuo Kondo

Yoko Masuzawa

Minoru Yamakado

Ryusuke Nakagawa

Norio Sasamori

Eiko Takahashi

Hidehiro Ichinose

Noriko Yasa

Keita Takamatsu

According to the method of evaluating stress of the present invention, amino acid concentration data on the concentration value of amino acid in blood collected from a subject to be evaluated is measured, and a stress state including at least depressive illness and major depressive illness in the subject is evaluated based on the concentration value of at least one of Lys, His, ABA, Asn, Phe, Leu, Ile, Val, Trp, Tyr and Met contained in the measured amino acid concentration data of the subject.

Stress evaluating apparatus, method, system and program and recording medium therefor

The present invention provides compositions having, as active ingredients, a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.

Anti-tumor composition

The present invention provides composition having as active ingredients a stilbene derivatively and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.

The present invention provides novel benzene compounds presented by the following formulas, and analogs thereof, that exert an ACC activity-inhibiting effect that is effective in the treatment of obesity, hyperlipemia, fatty liver, hyperglycemia, impaired glucose tolerance, diabetes, diabetic complications (diabetic peripheral neuropathy, diabetic nephropathy, diabetic retinopathy, and diabetic macroangiopathy, hypertension, arteriosclerosis), hypertension, and arteriosclerosis. 

Benzene compounds

The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors, particularly for the treatment of solid or malignant tumors and thus methods of cancer and tumor treatment using the composition are also provided.

Stilbene compounds of the following formula (I) or their pharmaceutically acceptable salts are effective as carcinostatics and of low toxicity: ##STR1## wherein X represents a hydrogen atom or a nitrile group, and Y represents an amino acid acyl group.

Stilbene compounds and pharmaceutical compositions containing them

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Kawasaki, Japan

Yukio Nihei