Ajinomoto Co., Ltd.

Fujitsu Corporation

Yukiko Mori

Hisao Ito

Osamu Kurahashi

Tsuyoshi Nakamatsu

Kenichi Hashiguchi

Takayuki Asahara

Kiyoshi Matsuno

Yoko Kuwabara

Yoko Asakura

Mikiko Suga

Kazuhiko Totsuka

Kiyohiko Nishi

Shuichi Endo

Yoshinori Hirao

Ayako Koizumi

Tomomi Aoki

A purine-derived substance is produced by culturing a bacterium belonging to the genuswhich is able to produce purine-derived substance and has been modified so that enzymatic activity of fructose bisphosphatase is decreased, and collecting the purine-derived substance from the medium or cells.

Purine-derived substance-producing bacterium and a method for producing a purine-derived substance

A purine-derived substance is produced by culturing abacterium which has an ability to produce a purine-derived substance and has enhanced activity of an enzyme of the oxidative pentosephosphate pathway. The purine-derived substance is produced in the medium or the bacterial cells, and can be collected from the medium or the bacterial cells.

Purine-derived substance-producing bacterium and a method for producing purine-derived substance

A purine-derived substance is produced by culturing a bacterium belonging to the genuswhich has an ability to produce a purine-derived substance and has been modified so that enzymatic activity of transaldolase is decreased in a medium to cause accumulation of a purine-derived substance in the medium or cells, and collecting the purine-derived substance from the medium or cells.

L-Arginine is produced by culturing a coryneform bacterium in which an arginine repressor involved in L-arginine biosynthesis is deleted by disrupting a gene coding for the repressor, and which has L-arginine producing ability in a medium to produce and accumulate L-arginine in the medium, and collecting the L-arginine from the medium.

Arginine repressor deficient strain of coryneform bacterium and method for producing L-arginine

A DNA fragment which encodes a polypeptide defined in the following (a) or (b), and a polypeptide defined in the following (c) or (d):

Carbamoyl-phosphate synthetase gene of coryneform bacteria and method for producing L-arginine

Cadaverine dicarboxylate is produced by performing an enzymatic decarboxylation reaction of a lysine solution while adding a dicarboxylic acid containing 4 to 10 carbons to the lysine solution to maintain pH of the solution at a level sufficient for the enzymatic decarboxylation reaction to occur, for example, 4.0 to 8.0.

Method for producing cadaverine dicarboxylate

A Computer Aided Design (CAD) system with a dimension line editing function manages a drawing involving dimension lines and displays the drawing on a display unit connected to a terminal. The system edits the drawing according to a specified one of the dimension lines. The system has a setting unit for interactively setting an objective dimension line through the terminal; a retrieving unit for retrieving, in the drawing, dimension lines that are in parallel with the objective dimension line; and an editing unit for editing drawing data corresponding to the objective and parallel dimension lines according to a change quantity entered for the objective dimension line. The CAD system only asks a user to specify an objective dimension line to be edited as well as a change quantity applied to the dimension line. According to the specified data, the CAD system edits drawing data corresponding to the objective dimension line as well as drawing data corresponding to dimension lines that are parallel to the objective dimension line. This CAD system never asks the user to specify endpoints of the dimension lines to be edited one by one, so that the user can efficiently edit drawing data involving many dimension lines.

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Kawasaki, Japan

Yukiko Mori