Teikoku Seiyaku Co., Ltd.

Teikoku Seiyaku Kabushiki Kaisha

Yukiko Inamoto

Takashi Kamakura

Shigeyuki Inamoto

Shigeyuki Takama

Akiya Yamada

Mitsuhiro Kawada

Takahiko Wato

Makoto Takahashi

Takehiko Ohura

Naoki Uchida

Masaaki Uchida

Kenichi Hattori

Akihiro Hasui

Kayo Tanigawa

Seiichiro Kawabata

Takefumi Hoshikawa

Misuzu Fujisawa

Misuzu Kadoriku

Wound bed preparation in a skin wound area can be carried out by using a hydrogel sheet, wherein the hydrogel sheet is prepared by spreading a hydrogel containing a water-soluble polymer, glycerin, and water on a two-layered laminated film consisting of a polyurethane film and a hydrophobic fiber and the moisture permeability of the hydrogel sheet is 200-2000 (g/m/24 h).

Method for using hydrogel sheet for treating wound

External preparations for treatment of painful skin wound having an analgesic activity which comprises acetylsalicylic acid or its pharmacologically acceptable salt as an active ingredient.

External preparation for treating painful skin wound

An apparatus and a method for simulatively measuring an environment in a microspace between human skin and a wound dressing. The simulative environment-measuring apparatus includes a constant temperature-and-humidity chamber (); a heat exchanger () disposed in the chamber; a constant temperature water bath () and a pump () for supplying warm water to the heat exchanger; and a container () set on the heat exchanger. The container holds a water retentive member () therein, and is covered with a water vapor diffusion-controlling member (). A microspace () formed between the water vapor diffusion-controlling member and a wound dressing () is a simulatively reproduced space between human skin and the wound dressing. A thin temperature-and-humidity sensor () is set in the microspace to measure temperature and humidity. When plural containers are used, the environments of plural wound dressings can be measured at once.

Apparatus for simulatively measuring environment of wound dressing on skin and measuring method therefor

Disclosed is a water-based adhesive skin patch which has excellent storage stability, can achieve excellent accumulation of butenafine hydrochloride contained therein on a patched area such as the skin and a nail, and has a high therapeutic effect. Specifically disclosed is a water-based adhesive skin patch containing butenafine hydrochloride, which is characterized by containing butenafine hydrochloride, glycol salicylate and propylene glycol in a water-containing gel ointment. Specifically, butenafine hydrochloride is dissolved in a mixed solution of glycol salicylate and propylene glycol, and the resulting solution is dispersed in a water-containing gel. Particularly, the mixing ratio of glycol salicylate to propylene glycol is 1:2 to 1:30.

Butenafine hydrochloride-containing aqueous patch

An external preparation containing acetylsalicylic acid or its pharmaceutically acceptable salt as an active ingredient for treating anal diseases having therapeutic activity on hemorrhoids (internal hemorrhoid, external hemorrhoid), hemorrhoidal disease owing to anal fissure and other anal diseases together with activity on pain and pruritus.

Therapeutic agent for hemorrhoidal disease

The present invention relates to an improved intravaginal preparation containing a physiologically active peptide, which comprises a physiologically active peptide, a sucrose fatty acid ester and an organic acid with a pharmaceutically acceptable carrier or diluent, by which the physiologically active peptide can be absorbed safely and efficiently.

Intravaginal preparation containing physiologically active peptide

A pharmaceutical composition comprising a physiologically active polypeptide, an absorption promoting agent consisting of a combination of an organic acid and a fatty acid sucrose ester in admixture with a pharmaceutically acceptable carrier or diluent, which is suitable for oral administration and for application to the oral cavity, by which the polypeptide can sufficiently be absorbed through the intestinal tract or the mucous membrane in the oral cavity and exhibit the physiological activities without being suffered from enzymolysis.

Physiologically active polypeptide-containing pharmaceutical composition

Oral pharmaceutical preparation released at infragastrointestinal tract

Growing community of inventors

Takamatsu, Japan

Yukiko Inamoto