Mitsui Chemicals, Inc.

Yukiko Asou

Hosei Shinoda

Hiroaki Tamatani

Sustained releasing drug comprising copolymers and process for preparing the same

Copolymer and process for preparing the same

There are here disclosed a resin composition comprising a block or a graft copolymer (A) having a polyamino acid as a hydrophilic segment (a- ), and a degradable polymer as a hydrophobic segment (a- ), and a resin (B); and a method of accelerating the hydrolysis of a resin and inhibiting the heat deterioration thereof by mixing this copolymer (A) with the resin (B).

Resin composition

A medical composition is here disclosed which comprises a hydroxy acid-based oligomer (A) and a drug (B), wherein the hydroxy acid-based oligomer (A) is an oligomer in which the carboxylic acid-terminals are at least partially esterified, and the oligomer (A) has a function of becoming pH 5 to 8 when administered into an organism, and the oligomer (A) shows fluidity at 25&deg; C. This composition sustainedly releases the drug (B) to deliver it into an organism by a syringe or the like, and scarcely gives rise to irritation, inflammation or the like.

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Kanagawa, Japan

Yukiko Asou