Canon Denshi Kabushiki Kaisha

Tokyo Medical and Dental University

Tokai National Higher Education and Research System

Yuki Morooka

Akira Matsumoto

Yoshifumi Okamoto

Yuji Miyahara

Hiroko Matsumoto

Tsumori Sato

Miyako Tanaka

Takayoshi Suganami

Kanata Shirotori

Yusuke Akaike

Shinji Beppu

Ryota Fujikawa

Tomohiro Tomaru

A sugar-responsive gel that is highly resistant to temperature changes, and a sugar-responsive drug delivery device including such a gel. The sugar-responsive gel, which comprises a gel composition including a monomer having a hydroxyl group in addition to a phenylboronic-acid-based monomer, can exhibit suitable temperature resistance. A sugar-responsive drug delivery device including such a sugar-responsive gel is less susceptible to the effects of temperature changes, and therefore can prevent undesirable excessive delivery of a drug such as insulin.

Temperature-resistant sugar-responsive gel

A coupling/uncoupling device includes a columnar member configured by a divided pair of semicircular members, and a pair of coupling members forming a circular holding section that holds the columnar member. The circular holding section includes a circular inner surface section with which an outer circumferential surface of the columnar member is in slide contact, the circular inner surface section being formed from inner circumferential surfaces of a semicircular section in one coupling member and a semicircular section in the other coupling member. The columnar member is configured to be rotatable in both clockwise and counterclockwise directions along the circular inner surface section about a reference position where a contact surface of the pair of coupling members and a dividing surface of the columnar member are flush with each other.

Coupling/uncoupling device

Growing community of inventors

Tokyo, Japan

Yuki Morooka