Daiichi Sankyo Company, Limited

Yuki Domon

Tsuyoshi Shinozuka

Hiroyuki Kobayashi

Sayaka Suzuki

Kyosuke Tanaka

Hiroko Kimoto

Asuka Kawamura

Yutaka Kitano

Kousei Shimada

Sakiko Takahashi

Naohisa Arakawa

Disclosed herein are therapeutic agents and/or preventive agents for pain or therapeutic agents and/or preventive agents for a sodium channel associated disease. The present invention provides compounds represented by the following formula (I) or pharmacologically acceptable salts thereof: 

Cycloalkane derivatives

It is intended to provide a therapeutic agent and/or a preventive agent for a respiratory disease or a therapeutic agent and/or a preventive agent for a sodium channel associated disease. The present invention provides a pharmaceutical comprising a compound represented by the following formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: 

Drugs for treating respiratory diseases

It is intended to provide a bicyclic &#x3b3;-amino acid derivative having excellent activity as an &#x3b1;&#x3b4; ligand. The present invention provides a compound represented by the general formula (I): wherein R, R, R, R, R, R, R, R, and Rare a hydrogen atom or the like; and Ris a hydrogen atom, a halogen atom, a C1-C6 alkyl group, or the like.

Bicyclic &#x3b3;-amino acid derivative

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Tokyo, Japan

Yuki Domon