Daiichi Sankyo Company, Limited

Yukari Onishi

Hideki Kobayashi

Kenjiro Ueda

Masahiro Konishi

Takeshi Honda

Akihiro Furukawa

Yumi Matsui

Takehiro Fukuzaki

Tetsuyoshi Matsufuji

Takayuki Baba

Makoto Mori

Atsushi Aoyagi

Masaharu Inui

Kunihiko Fujii

Tetuyoshi Matsufuji

The present invention relates to a compound represented by the following general formula (I) or a pharmacologically acceptable salt thereof having an excellent effect of inhibiting 11&#x3b2;-hydroxysteroid dehydrogenase type 1: General formula (I) wherein Rrepresents a phenyl group that may be substituted with 1 to 5 group(s) independently selected from substituent group A or a heterocyclic group that may be substituted with 1 to 4 group(s) independently selected from substituent group A; Rindependently represents a halogen atom or a C-Calkyl group; n represents an integer of 0 to 2; and substituent group A represents the group consisting of halogen atoms, C-Calkyl groups, and so forth.

Tetrahydrothiazepine derivative

The present invention relates to a compound or a pharmacologically acceptable salt thereof having superior glucokinase activating activity, and is a compound represented by general formula (I), or pharmacologically acceptable salt thereof: [wherein,

Phenylpyrrole derivative

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Kanagawa, Japan

Yukari Onishi