Astellas Pharma Gmbh

Yukari Koya

Jun Takasaki

Masazumi Kamohara

Hirotsugu Tanaka

Atsuo Yonezawa

Eiji Yoshimi

Anti-human NGF antibodies are useful for treating pain.

Method of treating pain with anti-human NGF antibody

[Task] To provide an anti-human NGF antibody or an antigen-binding fragment thereof that is excellent in safety by reducing the risk of side effects such as effects on a fetus and thrombus formation while maintaining high neutralizing activity, and to provide means for preventing or treating various diseases in which human NGF is involved in the formation of pathological conditions, by using the antibody or the antibody-binding fragment thereof. [Means for Resolution] An anti-human NGF antibody Fab' fragment comprising a heavy-chain variable region consisting of an amino acid sequence shown by SEQ ID NO:6 and a light-chain variable region consisting of an amino acid sequence shown by SEQ ID NO:4.

Growing community of inventors

Tokyo, Japan

Yukari Koya