Daiichi Sankyo Company, Limited

Suntory Limited

National Cerebral and Cardiovascular Center

University of Miyazaki

Yujiro Hayashi

Kenji Kangawa

Hisayuki Matsuo

Shoji Tanaka

Hiroshi Nakazato

Takehiro Oshima

Keiko Nakahara

Shinzo Oikawa

Noboru Murakami

Yasunori Tawaragi

An object of the present invention is to provide a therapeutic agent for accelerating recovery to accelerate a return to normal physical conditions by administering to an animal not in good health and under medical treatment, a treatment method, and the like. There is provided a therapeutic agent for accelerating recovery for animal use to accelerate the improvement of a physical condition of an animal under medical treatment which has a decreased activity (vigor) and is exhausted, which contains ghrelin or a derivative thereof or a pharmaceutically acceptable salt thereof as an active ingredient and improves one or more of evaluation parameters consisting of activity (vigor), blood cell test values, biochemical test values, body temperature, the degree of anger or anxiety, and respiratory rate.

Therapeutic agent for accelerating recovery of animal under medical treatment

Disclosed is a DNA fragment comprising a base sequence coding for a peptide occurring in human atrium cordis and having diuretic action or a precursor of the peptide, plasmids containing the DNA fragment, microorganisms transformed with the plasmid, and a process for production of the peptide using the transformant. Also disclosed is a new peptide consisting of 126 amino acids occurring in human atrium cordis and a precursor thereof. The peptide has notable diuretic action and hypotensive or antihypertensive actions.

Peptide and gene coding for same

Growing community of inventors

Kobe, Japan

Yujiro Hayashi