Shanghai Mabgeek Biotech. Co., Ltd

Yujing Yuan

Chenghai Zhang

Jinlin Guo

Yang Wang

Wei Dang

Lingqiao Zhu

Yipan Wu

Qiuling Zou

Shun Hu

Disclosed are an antibody that can bind to human MASP-2, a preparation method therefor and an application thereof. The anti-human MASP-2 antibody of the present invention can specifically bind to human MASP-2, has good biological activity of inhibiting the cleavage of C4 and the generation of C3b, and can be applied in the treatment of MASP-2 related diseases, such as IgA nephropathy.

Anti-human MASP-2 antibody, preparation method therefor and application thereof

The present invention discloses an antibody capable of binding to human interleukin 4 receptor alpha (hIL-4R alpha) and a preparation method and application thereof. The anti-hIL-4R alpha antibody can specifically bind to hIL-4R alpha, has good effects for inhibiting IL-4 and IL-13-induced cell line proliferation and the like, and can be applied to treatment of IL-4R alpha related diseases, such as immune-mediated inflammatory diseases.

Anti-human interleukin-4 receptor alpha antibody and preparation method and application thereof

Growing community of inventors

Shanghai, China

Yujing Yuan