Yoshitomi Pharmaceutical Industries, Ltd.

Yuji Ono

Tohru Nakao

Yasuto Morimoto

Masahiro Bougauchi

Takanori Oe

Hiroshi Tanaka

Kazuyuki Kawasaki

Minoru Obata

Tohru Nakajima

A condensed thiophene compound represented by general formula: ##STR1## or a pharmaceutically acceptable salt thereof, wherein ring S represents a thiophene ring; R.sup.1 represents hydrogen, halogen, alkyl, etc.; R.sup.2 represents hydrogen, alkyl, acyl, etc.; G represents --CH.sub.2 --, --CH(OH)--, --CO--, etc.; Q represents alkylene; T represents --N(Rb)(Rc) (wherein Rb, Rc represents each alkyl etc.; or alternatively Rb and Rc are combined together to form cyclic amino); D represents --CH.sub.2 -- or --S--; A and B represent each carbonyl or thiocarbonyl, or are null; and m and n represent each 0, 1 to 4, provided that m+n represents an integer of 4 or less. This compound is useful as an antipsychotic drug having a reduced extrapyramidal side effect.

Condensed thiophene compound and pharmaceutical use thereof

Thiophene compound

A novel pyridine compound of the formula ##STR1## wherein each symbol is as defined in the specification, or a salt thereof which exhibit inhibitory activity or prolylendopeptidase and a pharmaceutical use thereof are disclosed.

Pyridine compounds and pharmaceutical use thereof

Growing community of inventors

Fukuoka, Japan

Yuji Ono