Terumo Kabushiki Kaisha

Yuichi Tada

Mizuho Hirao

Suguru Hata

Akihiro Takahashi

Tomonori Hatta

Takao Anzai

Kosuke Nishio

Yasushi Kinoshita

Atsuhiko Nogawa

Yuji Nakagawa

Yuki Itoh

Mizuho Shiraishi

Ayaka Akutagawa

Michiyo Tsubooka

Takako Matsuno

Takashi Kitaoka

Takahiro Chida

Wataru Karino

A medical device for removing an intravascular thrombus includes: a rotatable tubular driving shaft in which a spiral-shaped carrier is provided on an inner surface thereof; a cutting part that is provided on a distal side of the driving shaft and cuts the thrombus; and an elongated resistive body that is disposed in a lumen of the driving shaft and can be rotated relative to the driving shaft.

Medical device and treatment method

Provided is a medical device capable of easily changing a position of the device inside a biological lumen and effectively removing a cut object. The medical device for removing the object in the biological lumen has a drive shaft, a cutting portion, a first housing that accommodates the drive shaft to be rotatable, a second housing that is rotatable with respect to the first housing, and a support portion that supports the first housing and the second housing. The second housing and the support portion relatively move along an axis to restrict relative rotation of the first housing and the second housing. The support portion supports the second housing to be rotatable around the axis.

Medical device having rotating shaft with lumen and sealing structure

A medical device is disclosed that can help prevent an object existing in a body lumen from clogging a lumen of an elongated member. The medical device including an elongated member having a lumen extending in an axial direction; an insertion member inserted in the lumen of the elongated member on a distal side of the lumen; and a breaking member fixed on an inner surface of the elongated member such that a gap is formed between the insertion member and the breaking member in the lumen of the elongated member on the distal side, and wherein the breaking member exerts a shearing force or a stretching force to the object by rotating relative to the insertion member while the object is between the insertion member and the breaking member.

Medical device

A medical device is disclosed that can help prevent a guide wire from coming into contact with a rotating body in the middle of performing a treatment and achieves improvement in the efficiency of cutting an object by the rotating body. The medical device has a sheath that is insertable into a body lumen, a rotatable hollow rotating body that is disposed to protrude toward a distal side of the sheath, and guide wire lumens into which a guide wire w is insertable in parallel with the sheath. A distal surface of the rotating body has corrugated portions.

Provided is a medical device capable of easily changing a position of the device inside a biological lumen and effectively removing a cut object. The medical device for removing the object in the biological lumen has a drive shaft, a cutting portion, a first housing that accommodates the drive shaft to be rotatable, a second housing that is rotatable with respect to the first housing, and a support portion that supports the first housing and the second housing. The second housing and the support portion relatively move along an axis to restrict relative rotation of the first housing and the second housing. The support portion supports the second housing to be rotatable around the axis, and restricts a relative movement and a relative inclination of the second housing and the support portion in a direction intersecting with the axis.

A medical device is capable of aspirating an object in a body lumen, while preventing the retention of the object therein, and effectively discharging the object. The medical device includes: a rotatable drive shaft having a lumen; a cutting portion fixed to a distal portion of the drive shaft to cut the object; and a housing that contains a proximal portion of the drive shaft and has a discharge port through which the cut object is discharged. The drive shaft has a proximal opening portion that extends around a portion of a circumference of the drive shaft to expose a discharge opening. The discharge port includes a discharge hole through which the cut object discharged through the discharge opening of the proximal opening portion is discharged from the housing, and a guide surface that protrudes toward the proximal opening portion to guide the cut object into the discharge hole.

A medical elongated body is disclosed that suppresses elongation in an axial direction while maintaining high flexibility and has high torque transmission capability even in a bent state. The medical elongated body includes a tube shaped body. The tube shaped body has a slit extending in a spiral shape while meandering, the slit is formed from a pair of a first opposing surface and a second opposing surface, the first opposing surface forms a first convex portion, the first convex portion has a first wide portion having a width wider in a circumferential direction Y, the second opposing surface forms a first concave portion which surrounds and accommodates the first wide portion, the first convex portion has a first plane portion and a first side portion connected to both end portions, and in a circumferential developed view, the first side portion and the first plane portion have tangential discontinuity.

Medical elongated body

A medical device is disclosed that can help prevent an object existing in a body lumen from clogging a lumen of an elongated member. The medical device including an elongated member having a lumen extending in an axial direction; an insertion member inserted in the lumen of the elongated member on a distal side of the lumen; and a breaking member fixed on an inner surface of the elongated member such that a gap is formed between the insertion member and the breaking member in the lumen of the elongated member on the distal side, and wherein the breaking member exerts a shearing force to the object by rotating relative to the insertion member while the object is between the insertion member and the breaking member.

A medical device to effectively remove an object, like an intravascular thrombus, in a body lumen includes: a rotatable tubular driving shaft; a cutting part that is provided on a distal side of the driving shaft, rotates together with the driving shaft, and cuts the thrombus; and a second cutting part that is disposed near the distal side of the driving shaft, inward of the cutting part.

A medical device has a rotatable drive shaft, a rotary body whose distal end includes a cutting edge for applying a cutting force to a stenosed site, and that is disposed on a distal side of the drive shaft so as to be rotated in conjunction with rotation of the drive shaft, and a distal member disposed in the rotary body. The distal member has a support portion extending to a distal side beyond a distal end of the rotary body, and configured to be capable of supporting the rotary body with respect to a blood vessel. The support portion is configured so that a distance from the rotary body is variable in a first direction (height direction) in which the rotary body is moved close to the stenosed site.

A medical device has a rotatable drive shaft, a rotary body that includes a cutting edge for applying a cutting force to a stenosed site, and that is disposed on a distal side of the drive shaft so as to be rotated in conjunction with rotation of the drive shaft, a switching portion whose distal end is disposed at a position protruding from the cutting edge, and a holding portion that holds the switching portion so as to move the switching portion on the same plane as the cutting edge or to a position away from the stenosed site beyond the cutting edge in accordance with a pushing force, when the switching portion is pushed against the stenosed site.

A medical device for removing an object within a living body lumen includes a rotatable tubular driven shaft having a leading-out hole opening in a proximal portion of the driven shaft, a cutting unit disposed on a distal side of the driven shaft, the cutting unit cutting an object while rotating together with the driven shaft, and a suction tubular body having a distal portion and a proximal portion, the distal portion of the suction tubular body being located within the driven shaft, the proximal portion of the suction tubular body being located outside the driven shaft and extending in a direction of separating from the driven shaft outward in a radial direction of the driven shaft.

A fibrosis-causing agent is highly effective in the fibrosis of tissues. The fibrosis-causing agent contains a fibrosis inducer and a fibrosis promoter. A fibrosis-causing agent dosage form and a method of administering the fibrosis-causing agent is also disclosed.

Fibrosis-causing agent

A method for treatment of chronic obstructive pulmonary disease includes occluding at least one of a bronchial tube and emphysema, and deciding whether or not a bypass has been formed by the occlusion.

Growing community of inventors

Kanagawa, Japan

Yuichi Tada