Nissui Pharmaceutical Co., Ltd.

Fuso Pharmaceutical Industries, Ltd.

Yuichi Oku

Yoshihiko Uesaka

Masahiro Asakura

Hirotsugu Uehara

Kanako Abe

Souji Eda

Kumiko Shinohara

Kazumasa Kamei

Yoko Otsuka

Yoshitatsu Tanaka

Norihiko Sugimoto

Yusuke Shibahara

Noriko Toyoda

Masayoshi Imagawa

Very simple, highly sensitive detection or quantification of target nucleic acids of interest has been achieved by: hybridizing mask oligonucleotides to regions in a single-stranded region of a nucleic acid to be assayed between which a region to be hybridized by an oligonucleotide probe is positioned, thereby opening the probe-hybridizing region and keeping the single-stranded region of the target nucleic acid stable, and then subjecting this nucleic acid having the single-stranded region to nucleic acid chromatography.

Nucleic acid detection or quantification method using mask oligonucleotide, and device for same

Polynucleotides which are produced by preadipocytes within 12 hours from the start of adipocyte differentiation induction and comprise a base sequence identical or at least 93% homologous to SEQ ID NO:1, or a base sequence identical to SEQ ID NO:9, or polynucleotides complementary to those polynucleotides, and proteins comprising an amino acid sequence identical or at least 96% homologous to the protein shown under SEQ ID NO:2 or comprising the amino acid sequence shown under SEQ ID NO:10 are provided.

Adipocyte differentiation-associated gene and protein

A housing for an immunochromatography apparatus capable of detecting the concentration of an analyte contained in a sample even if it is relatively low in concentration is provided. In the housingof immunochromatography apparatus having an observation window, the observation windowof the housingis made of a colored transparent plastic material having a transmittance of at least 20%, preferably at least 40%, so that a detection line displayed on a developing stripcontained therewithin can be seen therethrough, the other portion of the housing than the observation windowis made of a colored transparent plastic material having a transmittance of at least 12%, and the observation windowand the housingare simultaneously and integrally molded out of the same plastic material.

Housing of immunochromatography apparatus

Providing an assay method capable of simultaneously determining the presence or absence of one or more species of biological substances or assaying the amounts thereof with a single assay device, a kit therefor and an assay device thereof. The amount thereof or the presence thereof is detected, by putting a liquid sample containing one or more species of analytes in contact to a reagent including one or more species of marker-labeled ligands and one or more species of nucleic acid-labeled ligands, to generate one or more species of complexes, developing the generated one or more species of complexes through capillary phenomenon in developing element in a sheet form, capturing the complexes through complementary nucleic acid binding onto anti-bond elements consisting of nucleic acids on detection zones and formed depending on each of one or more species of nucleic acids immobilized on the detection zone , thereby capturing a complex depending on the analyte species, through the complementary binding between the anti-bond element and the bond element, to form an independent band and to assay the amount or the presence on the detection part.

Analytical method, kit, and apparatus

Method and reagent for simultaneously assaying one or more ligands in a

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Ibaraki, Japan

Yuichi Oku