Tsinghua University

Simpson Biotech Co., Ltd

Yuh-Ju Sun

Margaret Dah-Tsyr Chang

Ping-Chiang Lyu

Shu-Chuan Lin

Wei-I Chou

Chia-Chin Sheu

A polysaccharide-protein binding model of SBD, and a fibril-forming 14-residue peptide consisting of XNNNXXNYQXXXXXwherein the Xand Xmean a pair of opposite charged amino acid residues, and the X, X, X, X, X, or Xmeans an amino acid residue is described. A mixture for diminishing a polysaccharide, comprising at least two starch binding domains (SBDs) and a polysaccharide in a helix form is also presented. A method of providing an oligosaccharide, and a method of producing an amyloid-like fibril and use thereof are further described.

Polysaccharide-protein binding model and nano-fibril formation of a starch binding domain

The present invention provides a method for identifying starch binding sites of starch binding domain in CBM family. The CBM family is consisting of CBM20, CBM21, CBM25, CBM26, CBM34, and CBM41. The method further comprises predicting starch binding sites of starch binding domain in CBM family using the identified starch binding sites of starch binding domain with same topology.

Starch binding domain and use thereof

A polysaccharide-protein binding model of SBD, and a fibril-forming 14-residue peptide consisting of X1NNNX2X3NYQX4X5X6X7X8, wherein the X1 and X8 mean a pair of opposite charged amino acid residues, and the X2, X3, X4, X5, X6, or X7 means an amino acid residue is described. A mixture for diminising a polysaccharide, comprising at least two starch binding domains (SBDs) and a polysaccharide in a helix form is also presented. A method of providing an oligosaccharide, and a method of producing an amyloid-like fibril and use thereof are further described.

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Hsinchu, Taiwan

Yuh-Ju Sun