Ethicon, Gmbh

Depuy Mitek, Inc.

Guangzhou Bioseal Biotech Co. Ltd

Johnson & Johnson China Ltd.

Guangzhou Bioseal Co., Ltd.

Depuy International Limited

Advanced Technologies and Regenerative Medicine, LLC

Cordis Corporation

Codman & Shurtleff, Inc.

Cordis Neurovascular, Inc.

Johnson and Johnson Vision Care, Inc.

Yufu Li

Dennis D Jamiolkowski

Shawn Thayer Huxel

Arindam Datta

Zhigang Li

Joseph Henry Contiliano

Dengmin Feng

Gregory R Whittaker

Lisa M Donnelly

Joan M Sullivan

J Jenny Yuan

Xiang Wan

Kevin L Cooper

Chunlin Yang

Murty Narayan Vyakarnam

Iksoo Chun

Raymond S Shissias

Yanhui Zhang

Guojun Ni

Ling Teng

Shuang Chen

David W Overaker

Mark B Roller

Mora Carolynne Melican

Ronald W Marsh

Nir I Nativ

Qiang Zhang

Richard Champion Davis, Iii

Glenn R Cook

Michael G Tokarski

Kelly R Brown

Deborah M Schachter

Jerome Riebman

Jenny J Yuan

Stephen Wohlert

Michael Logue

Randolph W Hubbell

James Eckhardt

Michael Elser

Sandra Wechsler

Steven Arnold

Juan A Lorenzo

Darren R Sherman

Nathan Stewart Cauldwell

Alireza Rezania

Angelo G Scopelianos

Robert Burgermeister

Yue Zhou

Vipul Bhupendra Dave

James M Peck

Pallassana V Narayanan

John Matonick

Emil Richard Skula

Dharmesh K Dubey

Hiep Quang Do

Mark C Zimmerman

Kevor S TenHuisen

Kevor Shane TenHuisen

John McAllen, Iii

Gwan-Ywan Lai

E Richard Skula

Aibin Yu

Jianping Yu

Matthew Gounis

Dharmesh Dubey

James Malcolm Peck

Angelo G Scopellianos

Mcallen Iii John John

Hiep Do

Richard Champion Davis Iii

The present invention is directed to hemostatic compositions comprising at least partially integrated agglomerated ORC fibers, fibrinogen, and thrombin and methods of forming a powdered hemostatic composition, comprising the steps of: forming a suspension of a mixture comprising particles of fibrinogen, thrombin, ORC fibers in a non-aqueous low boiling solvent; spraying the suspension through a nozzle onto a substrate, allowing the non-aqueous solvent to evaporate; separating from the substrate and sieving the composition.

Hemostatic compositions and methods of making thereof

The present invention is directed to a flowable hemostatic paste comprising a crosslinked carboxymethyl cellulose and at least one non-toxic dispersant. More specifically the present invention relates to a hemostatic paste containing citric acid cross-linked CMC, which is suspended or dispersed as a powder in a mixture of a first non-toxic glycerol-containing hygroscopic dispersant and a second non-toxic alcohol functionalized dispersant comprising propylene glycol or 1,3-butanediol.

Hemostatic paste and methods of making thereof

The present invention is directed to hemostatic compositions comprising at least partially integrated agglomerated ORC fibers, fibrinogen, and thrombin and methods of forming a powdered hemostatic composition, comprising the steps of: forming a suspension of a mixture comprising particles of fibrinogen, thrombin, ORC fibers in a non-aqueous low boiling solvent, agitating and shearing said suspension in a high shear mixing reactor, adding water to allow particles to agglomerate, allowing the non-aqueous solvent to evaporate, drying and sieving the composition; and thus forming the powdered hemostatic composition.

The present invention relates generally to agents and devices for promoting hemostasis and tissue sealing and, more particularly, to hemostatic pads comprising bioabsorbable scaffolds that can deliver lyophilized hemostasis promoting proteins, such as fibrinogen and thrombin, to a wound site or injured organ or tissue.

Hemostatic pad assembly kit and method

The present invention is directed to hemostatic compositions comprising at least partially integrated agglomerated oxidized regenerated cellulose (ORC) fibers, fibrinogen, and thrombin and methods of forming a powdered hemostatic composition, comprising the steps of: forming a suspension of a mixture comprising particles of fibrinogen, thrombin, ORC fibers in a non-aqueous low boiling solvent; spraying the suspension through a nozzle onto a substrate, allowing the non-aqueous solvent to evaporate; separating from the substrate and sieving the composition.

The present invention relates to surgical instruments and methods for enhancing properties of tissue repaired or joined by surgical staples and, more particularly to surgical instruments and methods designed to enhance the properties of repaired or adjoined tissue at a target surgical site, especially when sealing an anastomosis between adjacent intestinal sections so as to improve tissue viability, prevent tissue infection, and to prevent leakage.

Anastomotic stapling reinforcing buttress and methods of deployment

An implantable medical device, which comprises a device substrate, a coating on the substrate which includes a drug, and a protective layer which overlies the coating. The protective layer comprises a polymer selected from the group consisting of polylactic acid, polyglycolic acid and a lactic acid/glycolic acid copolymer having a weight average molecular weight of not more than 40,000.

Implantable medical device

The present invention relates to circular anastomosis stapler and kits comprising reinforcing buttress materials and fixation tools that are slidably installed on the anvil shaft of such staplers which provides a temporary mechanical fixation of a reinforcing buttress to the anvil surface of a circular stapler during the insertion of the anvil into the tubular tissue. When the anvil, loaded with the buttress, is in the desired location, the fixation tool is pulled back along the anvil shaft and removed. The shaft is then connected to the stapling head and the stapling is performed. The present invention also relates to methods for using the kits and devices therein.

Temporary fixation tools for use with circular anastomotic staplers

The present invention provides a fixation device that includes an elongate shank defining a longitudinal axis and having at least one engaging member for applying the fixation device within tissue and securing the fixation device in the tissue once implanted formed thereon, and a drive head having a proximal end, a distal end and a radial cross-sectional geometry, where the drive head is mated to the elongate shank, and includes at least one anti-rotational member integral therewith, Fixation device kits utilizing the fixation device, and methods of fixation in tissue are also provided.

Medical fixation devices with improved torsional drive head

An implantable medical device, which comprises a device substrate, a coating on the substrate which includes a drug which is highly soluble in water, and a protective layer which overlies the coating. The protective layer comprises a polymer selected from the group consisting of polylactic acid, polyglycolic acid and a lactic acid/glycolic acid copolymer having a weight average molecular weight of not more than 40,000.

A method of replacing an ACL with a graft. The method provides for the drilling bone tunnels in a femur and a tibia. A replacement graft is provided having first and second ends. A biodegradable composite screw is provided. The screw is made from a biodegradable polymer and a bioceramic or a bioglass. At least one end of the graft is secured in a bone tunnel using the biodegradable composite screw.

Method of performing anterior cruciate ligament reconstruction using biodegradable interference screw

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Bridgewater, NJ, United States of America

Yufu Li