Other

Toshiba Medical Systems Corporation

Xiamen Nuokangde Biological Technology Co., Ltd.

Yufei Li

James A Moore

Steven M Cramer

Guhan Jayaraman

Amitava Kundu

Yong Sun

Qilin Xiao

Zhu Li

Xu Yan

Qinbin Li

Yunpeng Tian

Wanyun Li

Zengzi Zhang

Haiyang Wang

Zhiliang Zhang

Jianghong Zhang

Ting Wu

The present disclosure discloses melatonin derivatives, a method thereof, and a use thereof. The method comprises: dissolving melatonin in a solvent, adding a catalyst while maintaining the solvent at 0&#xb0; C. to obtain a first reaction solution, stirring the first reaction solution, adding reactants in the first reaction solution, continually stirring at room temperature or at refluxing reaction temperature until, when analyzing by thin layer chromatography, the first reaction solution is fully reacted, quenching the reaction with ice water, concentrating the first reaction solution to obtain a residue of the first reaction solution, and purifying the residue of the first reaction solution by column chromatography to obtain the melatonin derivatives.

Melatonin derivatives, method thereof, and use thereof

The present invention discloses a medical image fusion apparatus and method. The medical image fusion apparatus comprises: a display unit configured to display a plurality of medical images in layers in one window on a screen, wherein the arrangement direction of the plurality of medical images is different from the extension direction of the plane on which each medical image exists; an operation detection unit configured to detect an operation of selecting the medical images to be fused from the plurality of medical images; and a fused image generation unit configured to generate a fused image of the medical images to be fused according to the selection operation, wherein the display unit is further configured to display the fused image in a predetermined region in the window.

Medical image display apparatus and method

A method for the purification of proteins by displacement chromatography on ion exchange media using low molecular weight displacers is disclosed. Several classes of low molecular weight anionic species are exemplified, including aromatic rings having sulfonic acid or carboxylic acid moieties attached thereon, sulfated sugar derivatives, anionic antibiotics, and dendrimeric polymers. Novel compounds useful as displacers are dendrimers of formula ##STR1## wherein R.sup.1 is lower alkyl, n is 2 to 6 and similar dendritic polymers based thereon.

Displacement chromatography of proteins using low molecular weight

A method for the purification of proteins by displacement chromatography on ion exchange media using low molecular weight displacers is disclosed. Several classes of low molecular weight, charged species are exemplified, including aminoacids, peptides, antibiotics and dendrimeric polymers. Novel compounds useful as displacers are dendrimers of formula ##STR1## wherein R.sup.1 is lower alkyl, n is 2 to 6, and X is a common counter anion and similar dendritic polymers based thereon.

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Beijing, China

Yufei Li